Results 51 to 60 of about 2,468,383 (309)

Drug management of oxidation-reduction state of the body in respiratory tract diseases (part 6)

Zdorovʹe Rebenka, 2018
The review of the literature presents mo­dern data on antioxidant and anti-inflammatory acti­vity of polyphenols, as well as their representatives curcumin and resveratrol in diseases of the respiratory system.
A.E. Abaturov, A.P. Volosovets, T.P. Borysova   +2 more
doaj   +1 more source

Clinical outcomes and treatment patterns of older adults with dementia-related psychosis by dementia type in the United States

BMC Geriatrics, 2022
Background Little is known about the incidence of clinical events and treatment patterns among older adults with dementia-related psychosis. Given that dementia-related psychosis comprises various dementia types, this study describes the incidence of ...
Joan Forns, Heather E. Danysh, Lisa J. McQuay, Mary Ellen Turner, Colleen Dempsey, Mary S. Anthony, George Demos, J. Bradley Layton   +7 more
doaj   +1 more source

Pharmaceutical Exports of Iran in OIC Region and Entering International Markets

Journal of Pharmacoeconomics and Pharmaceutical Management, 2023
There are various pharmaceutical companies in Iran with high potential. Due to the lack of business with international markets for exports, Iranian pharmaceutical products are mostly traded in domestic markets. Despite numerous studies on pharmaceutical
Setareh Akhtarshenas, Hoda Yasini, Hossein Rastegar   +2 more
doaj   +1 more source

Therapeutic Apheresis for Intravenous Methylprednisolone‐Refractory Neuromyelitis Optica Spectrum Disorder: Clinical and Radiological Outcomes in a Single‐Center Case Series

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi, Daisuke Katagiri, Takeyuki Watadani, Shunichi Matsuda, Hiroshi Kaneko, Noritoshi Arai   +5 more
wiley   +1 more source

Analysis of Medication Inventory System for Intensive Care Unit: A Hospital Example

Türk Yoğun Bakim Derneği Dergisi
Objective: Optimizing health benefits becomes essential given the limitations of universal healthcare resources. Therefore, this study aims to conduct an always, better, and control (ABC) and vital, essential, and desirable (VED) analysis of medications ...
Alkan Durmuş, Özlem Öner, Ali Necati Gökmen   +2 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Ustekinumab for the treatment of psoriatic arthritis: an update. [PDF]

, 2014
Psoriatic arthritis occurs in 30% of psoriasis patients, and the treatment can be challenging in some patients. Recently, the US Food and Drug Administration approved ustekinumab, a fully human monoclonal antibody, for the management of psoriatic ...
Davari, Parastoo, Fazel, Nasim, Kamangar, Faranak, Leo, Michael S   +3 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Management of Chronic Heart Failure in Dialysis Patients: A Challenging but Rewarding Path

Reviews in Cardiovascular Medicine
Chronic heart failure (CHF) is a common complication and cause of death in dialysis patients. Although several clinical guidelines and expert consensus on heart failure (HF) in the general population have been issued in China and abroad, due to abnormal ...
Luxuan Guo, Yue Ji, Tianhao Sun, Yang Liu, Chen Jiang, Guanran Wang, Haitao Xing, Bo Yang, Ao Xu, Xian Xian, Hongtao Yang   +10 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source