Results 61 to 70 of about 2,468,383 (309)

Application progress on mobile health in drug management of patients with chronic diseases

Huli yanjiu, 2020
This paper analyzed and summarized relevant researches on the application of mobile health in drug management of patients with chronic diseases，such as its origin and development， application methods，effect evaluation，patients' attitude towards it and ...
PENG Yihang, XIE Liling
doaj  

Management of intestinal transplantation in humans [PDF]

, 1992
We report here the clinical experience and management guidelines for the nine consecutive cases who received either an isolated small intestinal graft (n = 1) or an intestine liver combination at the University of Pittsburgh, with FK 506 being the basic ...
Abu-Elmagd, K, Block, J, Casavilla, A, Demetris, J, Fung, JJ, Goldbach, B, Iwaki, Y, Nakamura, K, Nikolaidis, N, Reyes, J, Starzl, TE, Todo, S, Tzakis, A, Van Thiel, DH, Warty, V   +14 more
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

City-wide Analysis of Electronic Health Records Reveals Gender and Age Biases in the Administration of Known Drug-Drug Interactions

, 2020
The occurrence of drug-drug-interactions (DDI) from multiple drug dispensations is a serious problem, both for individuals and health-care systems, since patients with complications due to DDI are likely to reenter the system at a costlier level.
Correia, Rion Brattig, de Araújo, Luciana P., Mattos, Mauro M., Rocha, Luis M.   +3 more
core   +1 more source

A Comprehensive Review on Dry Eye Disease: Diagnosis, Medical Management, Recent Developments, and Future Challenges [PDF]

, 2015
Dry eye syndrome (DES) or keratoconjunctivitis sicca (KCS) is a common disorder of the tear film caused by decreased tear production or increased evaporation and manifests with a wide variety of signs and symptoms.
Askarkar, S, Momin, M, Nighojkar, P, Phadatare, S, Singh, Kamalinder   +4 more
core   +2 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Analysis of Health Literacy level and its Influencing Factors among the Elderly in a Certain City of China [PDF]

SHS Web of Conferences
Objective To understand the health literacy level and its influencing factors of elderly in Guangzhou, so as to provide scientific evidence for formulating effective intervention measures and policies.
Guo Yintong, Li Zhuangwei, Song Hui, Jiang Dan, Dong Jian   +4 more
doaj   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

A Comparison Study on the Health Literacy of Elderly in A Certain city of China in 2021 and 2023 [PDF]

SHS Web of Conferences
Objective To compare the difference between the health literacy level of elderly in Guangzhou in 2021 and 2023, and thus to provide government and institutions with a scientific data for enhancing health literacy level. Methods Two surveys were conducted
Guo Yintong, Song Hui, Jiang Dan, Dong Jian   +3 more
doaj   +1 more source

After Heparin: Protecting Consumers From the Risks of Substandard and Counterfeit Drugs [PDF]

, 2011
Based on case studies, examines globalization and quality management trends in pharmaceutical manufacturing, barriers to Federal Drug Administration oversight, and the security of pharmaceutical distribution.

core