Results 91 to 100 of about 86,096 (311)

2025: A Bright Year Ahead for Future Pharmacology

Future Pharmacology
As 2024 is coming to an end, let us reflect on Future Pharmacology’s achievements to better understand what is promising to be a bright year ahead [...]
Fabrizio Schifano
doaj   +1 more source

Drug misuse: opioid detoxification.

, 2007
NICE has produced two guidelines on drug misuse – ‘Drug misuse: psychosocial interventions’ (NICE clinical guideline 51) and ‘Drug misuse: opioid detoxification’ (NICE clinical guideline 52). They cover: • the support and treatment people can expect to

core  

Chronic alcohol consumption compromises gut barrier integrity and promotes endotoxemia: Implications for sepsis susceptibility in immunocompromised hosts

Animal Models and Experimental Medicine, EarlyView.
Chronic alcohol exposure disrupts intestinal barrier integrity, resulting in a leaky gut and enhanced translocation of lipopolysaccharide (LPS) and microbial products into the systemic circulation. Alcohol‐induced endotoxemia drives exaggerated pro‐inflammatory responses, mitochondrial damage, and activation of the cGAS–STING pathway, particularly in ...
Thansita Bhunyakarnjanarat, Chatsuree Suksamai, Dhammika Leshan Wannigama, Kent Doi, Wiwat Chancharoenthana, Asada Leelahavanichkul   +5 more
wiley   +1 more source

2023: The Best Year Ever for Future Pharmacology (and Even Better Years to Come)

Future Pharmacology
The end of any year provides an opportunity to reflect on the past, and in particular, the past twelve months [...]
Fabrizio Schifano
doaj   +1 more source

Drug misuse: psychosocial interventions.

, 2007
NICE has produced two guidelines on drug misuse – ‘Drug misuse: psychosocial interventions’ (NICE clinical guideline 51) and ‘Drug misuse: opioid detoxification’ (NICE clinical guideline 52). They cover: • the support and treatment people can expect to

core  

Animal research in the UK: Regulation, implementation, welfare and development of new approach methodologies

Animal Models and Experimental Medicine, EarlyView.
Scientific research with animals in the UK is regulated by the Animals (Scientific Procedures) Act 1986 with the National Centre for the Replacement, Refinement and Reduction of Animals in Research providing support for best practice and facilitating development of new approach methodologies.
Ewan St. John Smith, James Bussell, Maggie Gentry, Elliot Lilley, Cathy Merry, Judy MacArthur Clark, William Reynolds   +6 more
wiley   +1 more source

COVID-19: The Hidden Impact on Mental Health and Drug Addiction

Frontiers in Psychiatry, 2020
Stefania Chiappini, Amira Guirguis, Amira Guirguis, Ann John, John Martin Corkery, Fabrizio Schifano   +5 more
doaj   +1 more source

Association Between Opioid Use and Emergency Department Visits for Spine-Related Disorders

Journal of Pain Research
Chijioke Okeke,1,2 Godwin Okoye,3 J Douglas Thornton1,2 1The Prescription Drug Misuse Education and Research (PREMIER) Center, College of Pharmacy, University of Houston, Houston, TX, USA; 2Department of Pharmaceutical Health Outcomes and Policy, College
Okeke C, Okoye G, Thornton JD
doaj  

Quantum Phenomena in Molecular and Biological Systems: A Decoherence‐Based Decision Framework With Falsifiable Predictions and a Failure‐Mode Taxonomy

Advanced Physics Research, EarlyView.
A physics‐grounded framework based on decoherence timescales (τ_dec vs τ_func), Markovian validity, and falsifiability criteria is applied across molecular systems to distinguish where quantum effects are necessary, marginal, or irrelevant. The analysis integrates quantum chemistry, biological quantum mechanisms, and quantum computing under a unified ...
Sarfaraz K. Niazi
wiley   +1 more source

Characterising incident opioid use among incident users of prescription sedative hypnotics: A national cohort study

BMJ Open
Objective To evaluate co-prescribing of sedatives hypnotics and opioids.Design Retrospective study evaluating the association of patient characteristics and comorbidities with coprescribing.Setting and participants Using the national Merative MarketScan ...
Hui Zhao, Harshil Patel, James Douglas Thornton, Eric Schaefer, Chan Shen, Douglas Leslie, Tyler Varisco, Mina Shrestha, Matthew Wanat, Randa Al Saadi   +9 more
doaj   +1 more source