Results 101 to 110 of about 9,044,537 (408)

A Comparative Study of Cerebral Oxygenation During Exercise in Hemodialysis and Peritoneal Dialysis Patients

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Cognitive impairment and exercise intolerance are common in dialysis patients. Cerebral perfusion and oxygenation play a major role in both cognitive function and exercise execution; HD session per se aggravates cerebral ischemia in this population. This study aimed to compare cerebral oxygenation and perfusion at rest and in mild
Marieta P. Theodorakopoulou   +10 more
wiley   +1 more source

Brief introduction in phenotypic and genetic differences of C57BL/6 and BALB/c mice substrains

open access: yesAnimal Models and Experimental Medicine
Experimental mice play a critical role in biomedical research. The phenotype and application of different substrains vary due to genetic differentiation and variation.
Lan Zhao, Jie Wei, Bingfei Yue
doaj   +1 more source

Apigenin reduces the suppressive effect of exosomes derived from irritable bowel syndrome patients on the autophagy of human colon epithelial cells by promoting ATG14

open access: yesWorld Journal of Surgical Oncology, 2023
Background Inflammatory bowel disease (IBS) is a chronic disorder of the gastrointestinal tract. Exosomes have been involved in various pathological processes including IBS. Apigenin has been reported to suppress inflammatory bowel disease (IBS). However,
Rui Fu   +4 more
doaj   +1 more source

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

open access: yesFEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Effectiveness of blood pressure control in a small community [PDF]

open access: yes, 1989
The aim of this study was to examine the degree of control of blood pressure with respect to individuals on anti-hypertensive drug therapy attending a Health Centre for repeat prescription.
Cacciottolo, Joseph M., Galea, Wilfred
core  

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

Mapping Evidence of Pharmacy Services for COVID-19 in China

open access: yesFrontiers in Pharmacology, 2020
ObjectiveTo explore the role of pharmacists and innovation of pharmacy interventions for COVID-19 patients in China.MethodsWe comprehensively searched PubMed and Chinese databases Sinomed, China National Knowledge Infrastructure to identify articles ...
Zhan-Miao Yi   +13 more
doaj   +1 more source

Characteristics of drug users who do or do not have care of their children

open access: yes, 2004
Aims - To compare the relative frequency of eight indicators of problem drug use and potentially adverse social circumstances in drug using parents and non-parents and to explore whether a profile based on these characteristics differs according to ...
Advisory Council on the Misuse of Drugs   +18 more
core   +1 more source

Immunsuppressiva-Medikamentenspiegelmessung – reine Routine? / Immunosuppressant drug monitoring – a routine undertaking? [PDF]

open access: yes, 2010
The quantitative assessment of immunosuppressant drug levels is still one of the most challenging therapeutic drug monitoring procedures in clinical routine. During the past years, several technical developments matured to useable methods. In addition to
Seger, Christoph, Vogeser, Michael
core   +1 more source

Voriconazole Therapeutic Drug Monitoring [PDF]

open access: yesJournal of the Pediatric Infectious Diseases Society, 2014
A 2-year-old boy being treated for acute lymphoblastic leukemia developed confusion and was found to have a mass on cranial imaging. A neurosurgical biopsy revealed an aspergilloma. Intravenous (iv) voriconazole is administered at 8 mg/kg per dose twice daily.
Zachary, Hoy   +3 more
openaire   +2 more sources

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