Results 181 to 190 of about 9,044,537 (408)

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Monitoring Ion Channel Function In Real Time Through Quantum Decoherence

, 2009
In drug discovery research there is a clear and urgent need for non-invasive detection of cell membrane ion channel operation with wide-field capability.
Arhem, B. Stadler, Baaken, Balasubramanian, Balasubramanian, Bannai, Bradac, C. D. Hill, Cole, F. Caruso, Faklaris, Forn  s, Hall, Ide, J. H. Cole, J. Wrachtrup, Jelezko, Kramer, L. C. L. Hollenberg, L. T. Hall, Lundstrom, Maze, Mueller, Neugart, P. Mulvaney, Rabeau, Reimhult, Steinert, Tikhonov, Yamazaki, Yu   +30 more
core   +2 more sources

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Therapeutic drug monitoring of Amikacin in hospitalized patients: A pilot study [PDF]

, 2022
Sanjay Jaiswal, Amit Agarwal, SP Singh, Prafull Mohan   +3 more
openalex   +1 more source

Consensus Guidelines for Therapeutic Drug Monitoring in Neuropsychopharmacology: Update 2017

Pharmacopsychiatry, 2017
C. Hiemke, N. Bergemann, H. Clement, A. Conca, J. Deckert, K. Domschke, G. Eckermann, K. Egberts, M. Gerlach, C. Greiner, G. Gründer, E. Haen, U. Havemann-Reinecke, G. Hefner, R. Helmer, G. Janssen, E. Jaquenoud, G. Laux, T. Messer, R. Mössner, Matthias J. Müller, M. Paulzen, B. Pfuhlmann, P. Riederer, A. Saria, B. Schoppek, G. Schoretsanitis, M. Schwarz, M. S. Gracia, B. Stegmann, W. Steimer, J. Stingl, M. Uhr, S. Ulrich, S. Unterecker, R. Waschgler, G. Zernig, Gabriele Zurek, P. Baumann   +38 more
semanticscholar   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

Drug monographs on drugs which are frequently analysed in the context of Therapeutic Drug Monitoring [PDF]

, 2017
In addition to the monographs which were published last year by the working group "Drug Monitoring” of the Swiss Society of Clinical Chemistry (SSCC) [1], new monographs have been written.
Baumann, Pierre, Fathi, Marc, Grignaschi, Nathalie, Magnin, Jean-Luc, Rentsch (President), Working group "Drug Monitoring” of the SSCC (Arbeitsgruppe Medikamente der SGKC): Katharina, Thormann, Wolfgang, Todesco, Liliane, Wenk, Markus, Werner, Dominique   +8 more
core  

Determination of the Effectiveness of Antibiotic Therapy by Conducting Therapeutic Drug Monitoring

, 2020
А. М. Казанова, Mikhail S. Chenkurov, Arina Kopaylo, М. А. Ивжиц, S. К. Zyryanov   +4 more
openalex   +2 more sources

Implementation and evaluation of adverse drug reaction monitoring system in a tertiary care teaching hospital in Mumbai, India [PDF]

, 2013
Dindayal Patidar, Mithun Singh Rajput, Nilesh Prakash Nirmal, Wenny Savitri   +3 more
openalex   +1 more source