Results 191 to 200 of about 8,631,498 (387)

ABC of monitoring drug therapy. Why monitor drug therapy? [PDF]

BMJ, 1992
Aronson, J, Hardman, M
openaire   +4 more sources

Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies

FEBS Open Bio, EarlyView.
Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa, Ilva Liekniņa, Svetlana Koteloviča, Ramona Petrovska, Gediminas Žvinys, Agne Petrosiute, Asta Zubrienė, Matīss Toms Laugalis, Vendija Skeltona, Juris Jansons, Madara Kreishmane, Edita Čapkauskaitė, Daumantas Matulis, Kaspars Tārs   +13 more
wiley   +1 more source

What drives hyperammonemic encephalopathy in AED users: monotherapy risks or polypharmacy perils?

Frontiers in Pharmacology
Background and objectivesHyperammonemic encephalopathy (HE) is a serious side effect linked to sodium valproate (VPA). Recent case studies indicate that newer antiepileptic drugs (AEDs) might also trigger HE, whether used alone or alongside VPA.
Qing Shan, Qing Shan, Lei Wang, Xia Liu, Yan Chen, Yan Chen, Bing Li, Bing Li, Yuhang Guo, Yuhang Guo, Qiang Fu, Jinmin Guo, Jinmin Guo   +12 more
doaj   +1 more source

Chronic Ventricular Cerebrospinal Fluid Sampling, Drug Injections, and Pressure Monitoring Using Subcutaneous Reservoirs in Monkeys

, 1977
James H. Wood, David G. Poplack, William J. Flor, Neal E. Gunby, Ayub K. Ommaya   +4 more
openalex   +1 more source

Therapeutic Drug Monitoring of Antiepileptic Drugs in Women with Epilepsy Before, During, and After Pregnancy

Clinical Pharmacokinetics, 2020
Inge J. Arfman, E. A. Wammes-van der Heijden, P. T. ter Horst, D. Lambrechts, I. Wegner, D. Touw   +5 more
semanticscholar   +1 more source

Knockout of the mitoribosome rescue factors Ict1 or Mtrfr is viable in zebrafish but not mice: compensatory mechanisms underlying each factor's loss

FEBS Open Bio, EarlyView.
Mitochondria contain two mitoribosome rescue factors, ICT1 and MTRFR (C12orf65). ICT1 also functions as a mitoribosomal protein in mice and humans, and its loss is lethal. Although Mtrfr knockout mice could not be generated, knockout zebrafish lines for ict1 and mtrfr were established.
Nobukazu Nameki, Chika Tomisawa, Soichiro Hoshino, Hidehiko Shimizu, Masashi Abe, Sho Arai, Kanako Kuwasako, Naoki Asakawa, Yusuke Inoue, Takuro Horii, Izuho Hatada, Masakatsu Watanabe   +11 more
wiley   +1 more source

Monitoring Drug Use in a Community [PDF]

, 1988
J. E. S. Parker, Martyn Gay
openalex   +1 more source

The Indirect Effects of Family Structure on Drug Use in Adolescents [PDF]

, 2010
This paper focuses on explaining the significant relationship between family structure and adolescent drug abuse. Significant differences in drug abuse frequency and patterns among adolescents living in two-parent, step-parent, and single-parent ...
Corsetti, Maureen
core   +2 more sources

Construction of hyperthermostable d‐allulose 3‐epimerase from Arthrobacter globiformis M30 using the sequence information from Arthrobacter psychrolactophilus

FEBS Open Bio, EarlyView.
d‐Allulose can be produced from d‐fructose by d‐allulose 3‐epimerase. Based on sequence homology information, we successfully engineered thermostable mutants with the protein engineering method. By integrating positive mutations, we constructed an enzyme that exhibits hyperthermostability without a loss in the activity.
Kensaku Shimada, Kouhei Ohtani, Pushpa Kiran Gullapalli, Kazuhiko Ishikawa   +3 more
wiley   +1 more source

An Algorithm for Monitoring and Managing Drug Hepatotoxicity

, 1974
Alan F. Hofmann, Johnson L. Thistle
openalex   +1 more source