Results 101 to 110 of about 3,856,896 (414)
Protein‐Like Polymers Targeting Keap1/Nrf2 as Therapeutics for Myocardial Infarction
Advanced Materials, EarlyView.We describe a Keap1 targeting protein‐like polymer (PLP) which activates Nrf2, an important cytoprotective transcription factor for relieving myocardial infarction‐induced oxidative stress. This PLP increases cell survival in vitro in multiple relevant cardiac cell types and elicits pro‐reparative responses, improving cardiac function in a preclinical ...
Joshua M. Mesfin +17 more
wiley +1 more source
Cocaine- and opiate-related fatal overdose in New York City, 1990–2000
BMC Public Health, 2007 Background In New York City (NYC), the annual mortality rate is higher for accidental drug overdoses than for homicides; cocaine and opiates are the drugs most frequently associated with drug overdose deaths. We assessed trends and correlates of cocaine-
Tardiff Ken +5 more
doaj +1 more source
Tides Need STEMMED: A Locally Operating Spatio-Temporal Mutually Exciting Point Process with Dynamic Network for Improving Opioid Overdose Death Prediction [PDF]
arXiv, 2022 We develop a Spatio-TEMporal Mutually Exciting point process with Dynamic network (STEMMED), i.e., a point process network wherein each node models a unique community-drug event stream with a dynamic mutually-exciting structure, accounting for influences from other nodes.
arxiv
Healing a Broken System: Veterans and the War on Drugs [PDF]
, 2012 This report examines the plight of returning veterans who struggle with incarceration and psychological wounds of war such as addiction and post-traumatic stress disorder -- and suggests reforms that could improve the health and preserve the freedom of ...
core
Advanced Materials, EarlyView.Upconversion nanoparticle‐covalent organic framework core–shell particles provide enhanced contrast for optoacoustic imaging by leveraging the optical absorption of upconversion luminescence within the covalent organic framework matrix. Beyond their role as contrast agents, these particles enable customizable therapeutic agent loading and release, as ...
Dong Wook Kim +8 more
wiley +1 more source
A qualitative study of overdose responses among Chicago IDUs
Harm Reduction Journal, 2008 Background Opioid overdose is a leading cause of death among injection drug users. Over half of injection drug users report at least one nonfatal overdose during their lifetime.
Bigg Dan +5 more
doaj +1 more source
International Journal of Population Data Science, 2022 Objectives There are critical periods of mortality risk at onset and cessation of opioid agonist treatment. We aim to determine whether non-fatal overdose followed the same pattern as fatal overdose, comparing the first 4 weeks of treatment and ...
Nicola Jones +6 more
doaj +1 more source
GA-SVM for Evaluating Heroin Consumption Risk [PDF]
arXiv, 2021 There were over 70,000 drug overdose deaths in the USA in 2017. Almost half of those involved the use of Opioids such as Heroin. This research supports efforts to combat the Opioid Epidemic by further understanding factors that lead to Heroin consumption.
arxiv
The Opioid Crisis in Rural and Small Town America [PDF]
, 2018 In this brief, authors Shannon Monnat and Khary Rigg examine rural versus urban differences in opioid mortality and identify challenges for dealing with the opioid crisis in rural areas.
Monnat, Shannon M, Rigg, Khary K
core +1 more source
Flexible 3D Kirigami Probes for In Vitro and In Vivo Neural Applications
Advanced Materials, EarlyView.A customizable and scalable approach to fabricate flexible 3D kirigami microelectrode arrays (MEAs) featuring up to 128 shanks, including surface and penetrating electrodes designed to interact with the 3D space of neural tissue, is presented. The 3D kirigami MEAs are successfully deployed in several neural applications, both in vitro and in vivo, and ...
Marie Jung +10 more
wiley +1 more source