Results 161 to 170 of about 3,856,896 (414)

Influence of the arterial elastic component on the response to balloon angioplasty in femoral arteries of a healthy porcine model

Animal Models and Experimental Medicine, EarlyView.
This study evaluates the role of elastin in vascular response 28 days after balloon angioplasty using uncoated and paclitaxel‐coated balloons in a healthy porcine model. The results show higher elastin content in external femoral arteries, which is inversely correlated with vascular injury, inflammation, smooth muscle cell loss, proteoglycan and fibrin
María Gracia de Garnica García, Marina Gil Bernabé, Claudia Pérez‐Martínez, Laura Mola Solà, Luis Duocastella Codina, María Molina Crisol, Alex Gómez Castel, Armando Pérez de Prado   +7 more
wiley   +1 more source

Characteristics of Suicides Caused by Drug Overdose in the State of Maryland

Journal of Forensic Science and Medicine, 2015
Suicidal drug overdose is a major public health issue. In the United States, every year more than 33,000 people commit suicides. Our study focused on the characteristics of suicide victims in the state of Maryland.
Ling Li, Xinbiao Liao, Guozhong Zhang, Daming Sun, Tiantong Yang, Keming Yun, Rebecca Phipps, Xiang Zhang, Mary G Ripple, David Fowler   +9 more
doaj   +1 more source

A mouse model of lung ischemia–reperfusion injury with reversible left hilar entrapment

Animal Models and Experimental Medicine, EarlyView.
A Novel Reversible Left Hilar Entrapment Model for Mouse Lung Ischemia‐Reperfusion Injury with Visual Tracheal Intubation and Live Knot Technique. Abstract Lung ischemia–reperfusion injury (LIRI), an acute lung injury syndrome triggered by lung transplantation or distal organ ischemia, has long been a difficult and hot issue in clinical research.
GuangDong Weng, Yao Chen, ShanQing Bao, ChengXin Zhang, WenHui Gong   +4 more
wiley   +1 more source

Combinatorial targeting of G‐protein‐coupled bile acid receptor 1 and cysteinyl leukotriene receptor 1 reveals a mechanistic role for bile acids and leukotrienes in drug‐induced liver injury

Hepatology, EarlyView., 2022
CHIN117 is a dual cysteinyl leukotriene receptor 1 (CYSLTR1) antagonist and G‐protein‐coupled bile acid receptor 1 (GPBAR1) agonist. In the liver, GPBAR1 and CYSLTR1 are coexpressed by liver sinusoidal endothelial cells (LSECs), HSCs, circulating monocytes/macrophages, and liver resident macrophages (Kupffer cells).
Michele Biagioli, Silvia Marchianò, Cristina di Giorgio, Rosalinda Roselli, Martina Bordoni, Rachele Bellini, Bianca Fiorillo, Valentina Sepe, Bruno Catalanotti, Chiara Cassiano, Maria Chiara Monti, Eleonora Distrutti, Angela Zampella, Stefano Fiorucci   +13 more
wiley   +1 more source

A Rapid and Simple Method for the Quantification in Human Plasma of Tricyclic Antidepressant Drugs Taken in Overdose [PDF]

, 1979
W. D. Mitchell, Sarah F. Webb, George R. A. Padmore   +2 more
openalex   +1 more source

Drug and Opioid-Involved Overdose Deaths — United States, 2013–2017

MMWR. Morbidity and mortality weekly report, 2018
The 63,632 drug overdose deaths in the United States in 2016 represented a 21.4% increase from 2015; two thirds of these deaths involved an opioid (1).
Lawrence Scholl, P. Seth, M. Kariisa, N. Wilson, G. Baldwin   +4 more
semanticscholar   +1 more source

A hepatoprotective experiment on taro vegetable (Colocasia esculenta (L.) Schott) flower employing animal models by mitigating oxidative stress

Animal Models and Experimental Medicine, EarlyView.
The antioxidant efficacy of Colocasia esculenta flower’s methanolic extract was assessed using 2,2′‐azino‐bis‐(3‐ethylbenzothiazoline‐6‐sulfonic) (ABTS) and 2,2‐diphenyl‐1‐picrylhydrazyl (DPPH) scavenging assay. The hepatoprotective effect was investigated by assessing liver injury indicators (amino transferase [ALT], aspartate amino transferase [AST],
Mahathir Mohammad, Fahmida Tasnim Richi, Rabiul Hossain, Md. Arafat, Pair Ahmed Jiko, Nazim Uddin Emon, Sayed Al Hossain Rabbi, Tirtha Khastagir, Md. Hemayet Hossain, Safaet Alam   +9 more
wiley   +1 more source

Methaqualone1 Overdose: Analytical Methodology, and the Significance of Serum Drug Concentrations [PDF]

, 1973
David N. Bailey, Peter Jatlow
openalex   +1 more source

Drug Overdose Deaths Involving Cocaine and Psychostimulants with Abuse Potential — United States, 2003–2017

MMWR. Morbidity and mortality weekly report, 2019
In 2016, a total of 63,632 persons died from drug overdoses in the United States (1). Drug overdose deaths involving cocaine, psychostimulants with abuse potential (psychostimulants), or both substances combined increased 42.4% from 12,122 in 2015 to 17 ...
M. Kariisa, Lawrence Scholl, N. Wilson, P. Seth, B. Hoots   +4 more
semanticscholar   +1 more source

Hydrophilic Particles Exit While Hydrophobic Particles Persist Following In Vivo Biodegradation of Nanoparticle‐Laden Polymeric Devices

Advanced NanoBiomed Research, EarlyView.
Functionalizing biomedical implants with nanoparticle contrast agents introduces imaging capabilities to devices, improving patient care by avoiding inherent complications. However, nanoparticle surface chemistry optimized for device manufacturing may not lead to efficient nanoparticle clearance from tissues.
Kendell M. Pawelec, Jeremy M. L. Hix, Matti Kiupel, Peter J. Bonitatibus Jr., Erik M. Shapiro   +4 more
wiley   +1 more source