Results 141 to 150 of about 92,382 (306)
Experience of heroin overdose among drug users attending general practice. [PDF]
, 2000 Heroin overdose is responsible for significant mortality. It has not previously been highlighted as an important prevention or care issue for general practitioners involved in the management of drug misuse.
Langton, Deirdre +2 more
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The International Journal of Health Planning and Management, EarlyView.ABSTRACT This paper explores the perspectives of mental health and substance use providers who supported people released from custody during the pandemic in Ontario, Canada, with a focus on service disruptions, adaptations, and experiences. We conducted 20 in‐depth qualitative interviews and analysed these using Applied Thematic Analysis.
Lucas M. Seuren +6 more
wiley +1 more source
From epi to policy: prescription drug overdose state health department training and technical assistance meeting : Atlanta, Georgia April 22 and 23, 2013 [PDF]
CS244293-APublication date from document properties.PDO_epi_to_policy_meeting-a.pdfThe challenges of the prescription drug overdose epidemic are apparent from simply looking at a map of the US.
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Overdose strategy ‘critical’ for Ireland. [PDF]
, 2015 Today is International Overdose Awareness ...
O'Keeffe, Cormac
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International Journal of Cancer, EarlyView.Mutual exclusivity and co‐occurrence of oncogenic mutations reflect functional antagonism or dependence and may inform therapeutic strategies. However, most studies overlook variant‐level patterns. In this comprehensive, cross‐cohort analysis of BRAF, KRAS, and EGFR mutation subtypes, the most significant mutual exclusivity pairs overlapped with ...
Freya Vaeyens +14 more
wiley +1 more source
iNew Medicine, EarlyView.PD alleviates APAP‐induced ALI by inhibiting the NLRP3 inflammasome signaling pathway. C/EBPβ is identified as a direct target via multimethod validation. PD promotes the deacetylation of C/EBPβ via Sirt1. The Sirt1/C/EBPβ/NLRP3 signaling axis is defined for PD's hepatoprotective effect.
Tian‐Yu Yang +6 more
wiley +1 more source
Background:12-step programs aim to address drug-related harms, like opioid overdose, via abstinence. However, abstaining from opioids can diminish tolerance, which increases risk for overdose death upon resumption.
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Interdisciplinary Medicine, EarlyView.Following traumatic brain injury, indole‐3‐propionic acid (IPA) directly targets the aryl hydrocarbon receptor on astrocytes in the peri‐lesional cortex; this suppresses interferon regulatory factor 1‐driven transcription of the E3 ubiquitin ligase RFFL (ring finger and FYVE‐like domain containing E3 ubiquitin protein ligase).
Ziwen Zhang +22 more
wiley +1 more source
Journal of Applied Toxicology, EarlyView.ABSTRACT Modafinil (2‐(benzhydrylsulfinyl)acetamide) is a psychostimulant commonly prescribed for sleep disorders such as narcolepsy, excessive daytime sleepiness, and obstructive sleep apnea. Recently, its use has extended beyond clinical indications, with neurotypical individuals adopting it as a smart drug to enhance alertness and cognitive ...
Luciane Dellazari da Silva do Prado +9 more
wiley +1 more source
Surveillance Report: Highlights from the Annual Surveillance Report of Drug-Related Risks and Outcomes United States, 2019 [PDF]
This is the third annual drug surveillance report summarizing the latest data at the national level for opioid prescribing patterns, drug use, nonfatal overdoses, and fatal overdoses related to the current drug overdose epidemic in the United ...
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