Results 161 to 170 of about 92,110 (306)

Citrus depressa peel extract and its polymethoxyflavones mitigate acetaminophen‐induced chronic liver injury in mice through antioxidant activation, epigenetic regulation, and gut microbiota modulation

open access: yesJournal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Preventing chronic liver damage is essential for maintaining overall health and reducing the risk of serious liver diseases. Acetaminophen (APAP) overdose can lead to severe liver damage due to oxidative stress, and citrus fruits are rich in bioactive compounds that may have health benefits.
Po‐Yao Tsai   +7 more
wiley   +1 more source

Deresuscitation Informed by Ultrasound in Patients with Septic Shock Trial

open access: yesJournal of Ultrasound in Medicine, EarlyView.
Objectives The venous excess ultrasound (VExUS) can be used at the point‐of‐care to identify venous overload and end‐organ congestion in an effort to individually tailor resuscitation and deresuscitation in patients with septic shock. Methods We conducted a pilot randomized controlled feasibility trial of VExUS‐guided fluid management in adult patients
Brendan Innes   +7 more
wiley   +1 more source

Predicting drug overdose and death after "before medically advised" hospital discharge. [PDF]

open access: yesCMAJ
Naik H   +11 more
europepmc   +1 more source

Annual Surveillance Report of Drug-Related Risks and Outcomes \u2013 United States, 2019

open access: yes
Over 700,000 people died in the United States from drug overdoses between 1999 and 2017, with 70,237 deaths in 2017 alone.1 Of these 70,237 deaths, 67.8% involved an opioid.1 The age-adjusted drug overdose death rate has significantly increased from 6.0 (

core  

Experience of heroin overdose among drug users attending general practice.

open access: yes, 2000
Heroin overdose is responsible for significant mortality. It has not previously been highlighted as an important prevention or care issue for general practitioners involved in the management of drug misuse.
Langton, Deirdre   +2 more
core  

Postoperative Effects of Celecoxib on Opioid Use and Pain Control After Benign Oropharyngeal Surgery

open access: yesThe Laryngoscope, EarlyView.
This study evaluated how the addition of celecoxib to a multimodal pain regimen following tonsillectomy + adenoidectomy, or uvulopalatopharyngoplasty (UPPP) + tonsillectomy affects postoperative opioid use and pain control. Patients who received celecoxib consumed significantly fewer opioids compared to the historic control group, with similar ...
Alana Platukus   +9 more
wiley   +1 more source

Overdose strategy ‘critical’ for Ireland.

open access: yes, 2015
Today is International Overdose Awareness ...
O'Keeffe, Cormac
core  

Long‐Term Outcomes of Patients Undergoing Cricothyrotomy at a Tertiary Care Level One Trauma Center

open access: yesThe Laryngoscope, EarlyView.
This retrospective study of 48 patients undergoing emergent cricothyrotomy (2014–2025) evaluated short‐ and long‐term outcomes and complications. Common complications included dysphagia, pneumonia, and dysphonia, with delayed conversion to tracheostomy associated with increased pneumonia risk; long‐term issues included persistent dysphagia, subglottic ...
Shivani Raizada   +6 more
wiley   +1 more source

Nonfatal Drug Overdose in a National Sample of Adolescents by Intent and Substance, Medicaid 2016-2020. [PDF]

open access: yesJ Am Acad Child Adolesc Psychiatry
Bushnell G   +5 more
europepmc   +1 more source

Increased expression of aromatase after focal cerebral ischemia: Relevance to neuroprotection and functional recovery

open access: yesNeuroprotection, EarlyView.
Abstract Aim Aromatase is the key enzyme in the biosynthesis of 17β‐estradiol, the most potent estrogen, which has pleiotropic neuroprotective properties. Aromatase levels increase in the brain after stroke, and its gene variants increase susceptibility to stroke. This study aims to determine whether aromatase overexpression improves stroke outcome and
Lindsay Gallagher   +8 more
wiley   +1 more source

Home - About - Disclaimer - Privacy