Results 131 to 140 of about 6,265,118 (288)
Background:Polysubstance involvement is increasing among fatal drug overdoses. However, little is known about the epidemiology of polysubstance drug overdoses.
core +2 more sources
Drug Overdose Surveillance and Epidemiology (DOSE) System are Used for Action [PDF]
The overdose epidemic affects people in every age group, sex category, race and ethnicity, and geographic area. Monitoring trends in emergency department (ED) visits and hospitalizations for overdose can provide timely data to inform drug overdose ...
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Investigating the Cytoskeleton of DRGs Using Cryo‐Electron Microscopy and Deep Learning
Cytoskeleton, EarlyView.ABSTRACT We describe a method for determining the ultrastructural organization of axons and varicosities of cultured dorsal root ganglion (DRG) neurons using cryogenic electron microscopy (cryo‐EM). Cryo‐EM reveals the dimensions, proximity, and overall organization of biological specimens in a near‐native state, avoiding artifacts of fixation and ...
M. Neal Waxham +3 more
wiley +1 more source
PCN ReportsAim This study examined the conditions of drug abuse and dependence as well as the psychosocial characteristics of patients transported to an emergency department for over‐the‐counter (OTC) drug overdose.
Saeko Kohara +6 more
doaj +1 more source
The processes of reform in Victoria’s alcohol and other drug sector, 2011-2014 [PDF]
, 2014 This paper explores issues and concerns related to the 2014 alcohol and other drug sector recommissioning process in Victoria. Overview In mid-2014, the Victorian Alcohol and Drug Association approached the Drug Policy Modelling Program, at the ...
Drug Policy Modelling Program
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Cytoskeleton, EarlyView.ABSTRACT We here describe mouse models with complementary homozygous Svil mutations. In skeletal muscle, Svil‐Mut mice express the Svil‐encoded N‐terminus fused to the βgal‐neo gene‐trap tag and lack the highly conserved archvillin C‐terminus; Svil‐KO mice lack expression of all known Svil‐encoded proteins; and Svil‐LoxP mice contain loxP sites for ...
Tara C. Smith +9 more
wiley +1 more source
Research shows intentional drug overdose is most common reason homeless people present at hospitals.
, 2019 A conference heard that street drugs are three times more common in intentional drug overdose scenarios involving homeless people than compared to those in a fixed residence......
Baker, Noel
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Clinical Pharmacology &Therapeutics, EarlyView.Clinical translation of novel therapies can be hindered by heterogeneity‐driven sample size inflation in late‐stage trials. In acetaminophen‐induced liver injury (APAP DILI), many patients recover spontaneously, diluting investigational drug efficacy signals.
Chris Humphries +8 more
wiley +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.Personalized dosing is particularly important for drugs with narrow therapeutic indices in geriatric patients, who exhibit substantial physiological variability and limited pharmacokinetic (PK) evidence to guide individualized dose selection. Valproic acid (VPA) is an effective treatment option for bipolar disorder in older adults, yet dosing largely ...
Yoo Jin Jang +2 more
wiley +1 more source
Poisoning and drug overdoses in the Emergency Department at Songklanagarind Hospital
Journal of Health Science and Medical Research (JHSMR), 2010 Objective: To study the prevalence of poisoning and drug overdoses in the Emergency Department (ED) Songklanagarind Hospital. Material and Methods: A Retrospective study from January 1, 2007 to December 31, 2007. The records of all patients who presented
Chaipluk Sriprapan +1 more
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