Results 31 to 40 of about 92,382 (306)

The implementation of overdose prevention sites as a novel and nimble response during an illegal drug overdose public health emergency. [PDF]

, 2019
BACKGROUND: Drug-related overdoses were declared a public health emergency in British Columbia, Canada in April, 2016 facilitating the scale-up of responses including rapid sanctioning and implementation of overdose prevention sites (OPSs).
Pagan, Flora, Pauly, Bernadette (Bernie), Wallace, Bruce, Pauly, Bernie   +3 more
core   +1 more source

Flash Assembloids: A Rapid Biofabrication of a Platform for Modeling Early Glioblastoma Invasion at the Glioblastoma–Brain Organoid Interfaces

Advanced Healthcare Materials, EarlyView.
This study presents a bioengineered assembloid (ASM) system combining glioblastoma (GBM) cells in oxidized alginate (OA) microgels with dorsal organoids (DOs). This model simulates brain tumor‐host interactions, revealing enhanced GBM invasion, altered gene expression, and aggressive infiltration patterns, demonstrating ASM as a valuable platform for ...
Chao Liang, Henry Robert Howard, Shihui Chen, Won‐Young Choi, Summer Cao, Arthur Chien, Kevin Zou, Michael Kassiou, Fabien Delerue, Ho Sang Jung, Yeonju Park, Young Mee Jung, Yong‐Dae Kwon, Karrie M. Kiang, Gilberto Ka‐Kit Leung, Ryohichi Sugimura, Ann‐Na Cho, Sang Jin Lee   +17 more
wiley   +1 more source

Attitudes and knowledge about naloxone and overdose prevention among detained drug users in Ningbo, China

Substance Abuse Treatment, Prevention, and Policy, 2012
Background To date there has been limited research on both the prevalence of overdose and drug user knowledge about overdose prevention and response methods in China.
Liu Yu, Bartlett Nicholas, Li Longhui, Lv Xiuyi, Zhang Yahai, Zhou Wenhua   +5 more
doaj   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

Evolving trends in drug overdose mortality in the USA from 2000 to 2020: an age-period-cohort analysisResearch in context

EClinicalMedicine, 2023
Summary: Background: Drug overdose deaths in the USA have increased rapidly in the past 20 years, and understanding patterns and trends in mortality is essential to develop policy responses.
Sayuri Fujita-Imazu, Jinzhao Xie, Bibha Dhungel, Xinran Wang, Yijing Wang, Phuong Nguyen, July Khin Maung Soe, Jinghua Li, Stuart Gilmour   +8 more
doaj   +1 more source

Extrusion Bioprinting for Wound Healing: Innovations in Functionalized Bioinks and Bioprinting Technology

Advanced Materials Technologies, EarlyView.
Extrusion‐based bioprinting (EBB) has emerged as a versatile biofabrication platform capable of precisely depositing bioinks composed of biomaterials, cells, and bioactive agents to generate patient‐specific, biomimetic skin constructs. This paper presents a state‐of‐the‐art and forward‐looking overview of EBB for wound healing, encompassing printing ...
Hien‐Phuong Le, Anh Tuan Trong Tran, Ammara Waheed, Tran Thanh Tung, Dusan Losic   +4 more
wiley   +1 more source

mGluR5 in ECCCK to BLA Circuit Modulates Depressive‐Like Phenotypes through CCK Signaling

Advanced Science, EarlyView.
Dysregulation of mGluR5 and CCK signaling contributes to major depressive disorder, yet circuit‐level mechanisms remain unclear. Here, the ECCCK→BLA pathway is identified as a critical regulator of affective behavior. mGluR5 modulates synaptic function and CCK signaling within this circuit, controlling stress susceptibility and depressive‐like states ...
Muhammad Asim, Huajie Wang, Gao Qianqian, Abdul Waris, Jufang He   +4 more
wiley   +1 more source

Drug overdose in the ED: a record linkage study examining emergency department ICD-10 coding practices in a cohort of people who inject drugs

BMC Health Services Research, 2018
Background Drug overdose is a leading cause of mortality and morbidity amongst people who inject drugs (PWID). Drug overdose surveillance typically relies on the International Classification of Diseases (ICD-10) coding system, however its real world ...
Rehana Di Rico, Dhanya Nambiar, Mark Stoové, Paul Dietze   +3 more
doaj   +1 more source

Relationship between tracheal intubation and the drugs used by patients with drug overdose due to self-harm

Journal of Pharmaceutical Health Care and Sciences, 2022
Background Tracheal intubation may be performed in patients with drug overdose due to self-harm; however, the details of the causative drug are unknown.
Kazuki Nagashima, Hiroyuki Hosono, Machiko Watanabe   +2 more
doaj   +1 more source

Non-fatal drug overdose among persons who inject drugs during first two years of the COVID-19 pandemic in New York City: Prevalence, risk factors

Drug and Alcohol Dependence Reports, 2023
Background: We examined non-fatal drug overdoses during the COVID-19 pandemic among persons who inject drugs (PWID) in New York City (NYC). Methods: We recruited 275 PWID through respondent driven sampling and staff outreach from Oct. 2021-Sept. 2022 and
Don Des Jarlais, Chenziheng Allen Weng, Jonathan Feelemyer, Courtney McKnight   +3 more
doaj   +1 more source