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Drug and Alcohol Dependence ReportsBackground: National trends indicate that drug-related deaths among Veterans have been increasing from 2010 to 2019. The present study involves a recent analysis of drug mortality data for a single large Veterans Affairs (VA) Healthcare System.
Benjamin I. Felleman +4 more
doaj +1 more source
Risk of Overdose-Related Death for People with A History of Incarceration
International Journal of Population Data Science, 2020 Introduction Epidemiologic studies have shown that people released from correctional facilities are at substantially increased risk of overdose-related death compared with the general population.
Wenqi Gan +4 more
doaj +1 more source
Slaying the Dragon: How the Law Can Help Rehab a Country in Crisis [PDF]
, 2015 Motor-vehicle-related deaths consistently topped the accidental death count in the United States for decades. In 2009, for the first time, drug poisoning took over as the number one accidental killer.
Kopf, Samantha
core +1 more source
Trends and characteristics of accidental and intentional codeine overdose deaths in Australia [PDF]
, 2015 Examines trends in codeine-related mortality rates in Australia, and the clinical and toxicological characteristics of codeine-related deaths. Abstract Objectives: To examine trends in codeine-related mortality rates in Australia, and the clinical and ...
Amanda Roxburgh +6 more
core +1 more source
Model‐Driven Optimization of Subcutaneous Polymer Prodrugs Achieves Cancer Remission in Mice
Advanced Healthcare Materials, EarlyView.A pharmacokinetics/pharmacodynamics (PK/PD) model was developed to evaluate multiple dosing regimens for subcutaneously administered water‐soluble polymer prodrug for cancer therapy. The model enabled prediction of in vivo performance and contributed to the optimization of anticancer efficacy.
Anne Rodallec +5 more
wiley +1 more source
BMC Health Services Research, 2018 Background Drug overdose is a leading cause of mortality and morbidity amongst people who inject drugs (PWID). Drug overdose surveillance typically relies on the International Classification of Diseases (ICD-10) coding system, however its real world ...
Rehana Di Rico +3 more
doaj +1 more source
Drug supply measures and drug overdose mortality in the era of fentanyl and stimulants
Drug and Alcohol Dependence Reports, 2023 Background: Illicitly-manufactured fentanyl and stimulants have replaced prescription opioids as the primary contributors to fatal overdoses in the United States (US), yet the street supply of these substances is challenging to quantify.
Manuel Cano +3 more
doaj +1 more source
Drug Overdose Rates Are Highest in Places With the Most Economic and Family Distress [PDF]
, 2018 In this brief, author Shannon Monnat examines county-level mortality data from the U.S. Centers for Disease Control and Prevention, pooled for 2006–2015, to gain insight into the U.S. drug overdose problem.
Monnat, Shannon M.
core +1 more source
Carbamazepine overdose after exposure to simethicone: a case report [PDF]
, 2008 Introduction Carbamazepine is an anticonvulsant drug and is also used as a treatment for patients with manic-depressive illness, post-herpetic neuralgia or phantom limb pain. The drug itself has many drug interactions. Simethicone is an antifoaming agent
Ozlem Guneysel +14 more
core +2 more sources
3D Soft Hydrogels Induce Human Mesenchymal Stem Cells “Deep” Quiescence
Advanced Healthcare Materials, EarlyView.Three‐dimensional soft hydrogels mimicking the bone marrow niche induce deep quiescence in human mesenchymal stem cells. Unlike 2D culture, 3D matrices halt proliferation, regulate cell‐cycle and quiescence markers, and downregulate mTORC1 signaling, preserving stem cell phenotype and therapeutic potential ex vivo.
David Boaventura Gomes +11 more
wiley +1 more source