Results 51 to 60 of about 164,580 (300)

Trends in drug overdose deaths among adults 65 years of age and older in Canada (2000–2022)

Drug and Alcohol Dependence Reports
Background: Although young adults and middle-aged adults have borne the brunt of the drug overdose crisis in Canada, older adults are also at an increased risk of harms.
Sameer Imtiaz, Farihah Ali, Nat Kaminski, Cayley Russell, Jürgen Rehm   +4 more
doaj   +1 more source

Healing a Broken System: Veterans and the War on Drugs [PDF]

, 2012
This report examines the plight of returning veterans who struggle with incarceration and psychological wounds of war such as addiction and post-traumatic stress disorder -- and suggests reforms that could improve the health and preserve the freedom of ...

core  

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

Estimated Number of Injection-Involved Overdose Deaths in US States From 2000 to 2020: Secondary Analysis of Surveillance Data

JMIR Public Health and Surveillance
BackgroundIn the United States, both drug overdose mortality and injection-involved drug overdose mortality have increased nationally over the past 25 years.
Eric William Hall, Patrick Sean Sullivan, Heather Bradley   +2 more
doaj   +1 more source

Cocaine- and opiate-related fatal overdose in New York City, 1990–2000

BMC Public Health, 2007
Background In New York City (NYC), the annual mortality rate is higher for accidental drug overdoses than for homicides; cocaine and opiates are the drugs most frequently associated with drug overdose deaths. We assessed trends and correlates of cocaine-
Tardiff Ken, Gross Charles, Piper Tinka, Bucciarelli Angela, Bernstein Kyle T, Galea Sandro   +5 more
doaj   +1 more source

The impact of the novel coronavirus disease (COVID-19) pandemic on drug overdose-related deaths in the United States and Canada: a systematic review of observational studies and analysis of public health surveillance data

Substance Abuse Treatment, Prevention, and Policy, 2021
Background There are preliminary indications that the trajectory of drug overdose-related deaths in North America has been exacerbated due to the novel coronavirus disease pandemic (COVID-19).
Sameer Imtiaz, Frishta Nafeh, Cayley Russell, Farihah Ali, Tara Elton-Marshall, Jürgen Rehm   +5 more
doaj   +1 more source

The Opioid Crisis in Rural and Small Town America [PDF]

, 2018
In this brief, authors Shannon Monnat and Khary Rigg examine rural versus urban differences in opioid mortality and identify challenges for dealing with the opioid crisis in rural areas.
Monnat, Shannon M, Rigg, Khary K
core   +1 more source

Vat Polymerization 3D Printing for Controlled Drug Release Applications

Advanced Materials Technologies, EarlyView.
ABSTRACT Vat polymerization (VP) 3D printing, a light‐based additive manufacturing technique, has emerged as a promising technique for fabricating complex drug delivery systems with high precision and spatial resolution. This layer‐by‐layer manufacturing process enables the creation of intricate geometries and customizable architectures, which are ...
Hafiz Busari, O. Thompson Mefford, M. Aaron Vaughn   +2 more
wiley   +1 more source

Chronic Hypoxia Disrupts Spermatogenesis Through ASXL2–EZH2–Mediated Microtubule Destabilization

Advanced Science, EarlyView.
This study reveals the mechanism by which chronic hypoxia impairs spermatogenesis via the ASXL2–EZH2 axis, hindering the transition of spermatids from round to elongated forms. Key findings reveal that under hypoxic conditions, downregulated ASXL2 expression reduces EZH2 binding to the CEP162 promoter, leading to decreased H3K27me3 modification and ...
Jun Yin, Mengjie Zhang, Wenying Liu, Wenlong Shen, Debao Li, Hongming Miao, Fang Deng, Gang Zhang, Yi Tian, Yi Zhang, Zhihu Zhao, Bing Ni   +11 more
wiley   +1 more source

Fentanyl-driven acceleration of racial, gender and geographical disparities in drug overdose deaths in the United States.

PLOS Global Public Health, 2023
We examine trends in drug overdose deaths by race, gender, and geography in the United States during the period 2013-2020. Race and gender specific crude rates were extracted from the final National Vital Statistics System multiple cause-of-death ...
Maria R D'Orsogna, Lucas Böttcher, Tom Chou   +2 more
doaj   +1 more source