Results 71 to 80 of about 6,265,118 (288)

Hydro‐ and Lipophilicity of Molecular‐Size‐Controlled Hydrogel Drug Carriers

Advanced Materials Technologies, EarlyView.
We investigate nano‐sized hydrogel drug carriers with tailored hydro‐ and lipophilicity. We design their encapsulation and structure‐forming capabilities and follow them in real time during fabrication using time‐resolved and in situ grazing incidence x‐ray scattering.
Elisabeth Erbes, Naireeta Biswas, Calvin J. Gavillet, Matthias Schwartzkopf, Krishnayan Basuroy, Qing Chen, Andrei Chumakov, Susann Frenzke, Marc Gensch, Korneliya Gordeyeva, Patrycja Kielb, Sonja Kirchner, Volker Körstgens, Peter Müller‐Buschbaum, Henrike M. Müller‐Werkmeister, Jan Rubeck, Sreevidya Thekku Veedu, Jose de Jesus Velazquez‐Garcia, Vivian Waclawek, Daniel Söderberg, Stephan V. Roth, Simone Techert   +21 more
wiley   +1 more source

New methodology to improve tracking of Veteran overdose deaths and characterization of a population of Veteran overdose decedents in San Diego County

Drug and Alcohol Dependence Reports
Background: National trends indicate that drug-related deaths among Veterans have been increasing from 2010 to 2019. The present study involves a recent analysis of drug mortality data for a single large Veterans Affairs (VA) Healthcare System.
Benjamin I. Felleman, Neal M. Doran, Octaviana Hemmy Asamsama, Elizabeth M. Oliva, Benjamin H. Han   +4 more
doaj   +1 more source

Notes from the Field: Trends in Gabapentin Detection and Involvement in Drug Overdose Deaths — 23 States and the District of Columbia, 2019–2020

MMWR. Morbidity and mortality weekly report, 2022
Gabapentin is an anticonvulsant medication, which is also approved by the Food and Drug Administration to treat postherpetic neuralgia, a painful complication of shingles, which results from reactivation of the varicella zoster virus.*,† Gabapentin is ...
Christine L. Mattson, Farnaz Chowdhury, Thomas P. Gilson   +2 more
semanticscholar   +1 more source

Optimized Ex Vivo Human Liver Slice Culture Maintains Extended Viability and Function for Hepatotoxicity Testing

Advanced Science, EarlyView.
An optimized ex vivo human liver slice culture system preserves tissue architecture, hepatocyte function, and immune‐stromal complexity for at least five days. By refining slice thickness, oxygenation, air‐liquid interface, and extracellular matrix support, the platform enables human‐relevant hepatotoxicity testing and mechanistic studies, offering a ...
Huiche Feng, Cinzia Esposito, Andrej Benjak, Matthias S. Matter, Miriam Cieri, Camilla De Carlo, Philipp Sedlaczek, Fabian Haak, Mattia Marinucci, Gabriel Fridolin Hess, Otto Kollmar, Mairene Coto‐Llerena, Luca Di Tommaso, Visar Vela, Lukas Bubendorf, Luigi M. Terracciano, Charlotte K. Y. Ng, Salvatore Piscuoglio   +17 more
wiley   +1 more source

Risk of Overdose-Related Death for People with A History of Incarceration

International Journal of Population Data Science, 2020
Introduction Epidemiologic studies have shown that people released from correctional facilities are at substantially increased risk of overdose-related death compared with the general population.
Wenqi Gan, Stuart Kinner, Chloé Xavier, Bin Zhao, Amanda Slaunwhite   +4 more
doaj   +1 more source

Estimated Number of Children Who Lost a Parent to Drug Overdose in the US From 2011 to 2021.

JAMA psychiatry
Importance Parents' overdose death can have a profound short- and long-term impact on their children, yet little is known about the number of children who have lost a parent to drug overdose in the US.
Christopher M. Jones, Kun Zhang, Beth Han, G. Guy, J. Losby, Emily B. Einstein, Miriam Delphin-Rittmon, Nora D. Volkow, Wilson M. Compton   +8 more
semanticscholar   +1 more source

Remote Magnetomechanical Neuromodulation Uncovers Therapeutic Mechanisms for Alleviating Parkinsonian Symptoms in Freely Moving Mice

Advanced Science, EarlyView.
Magnetomechanical neuromodulation using magnetic nanodiscs enables remote activation of neurons. In a hemiparkinsonian mouse model, alternating magnetic fields actuate the nanodiscs to generate torque that opens mechanosensitive ion channels within the subthalamic nucleus, thereby modulating basal ganglia motor circuitry.
Anouk Wolters, Lorenzo Signorelli, Christian Herff, Sophia Gimple, Renzo Riemens, Gunter Kenis, Kim Rijkers, Hamed Shabani, Jyh‐Jang Sun, Yasin Temel, Hans Clusmann, Danijela Gregurec, Sarah‐Anna Hescham   +12 more
wiley   +1 more source

Trends in drug overdose deaths among adults 65 years of age and older in Canada (2000–2022)

Drug and Alcohol Dependence Reports
Background: Although young adults and middle-aged adults have borne the brunt of the drug overdose crisis in Canada, older adults are also at an increased risk of harms.
Sameer Imtiaz, Farihah Ali, Nat Kaminski, Cayley Russell, Jürgen Rehm   +4 more
doaj   +1 more source

Experience of Personal Loss Due to Drug Overdose Among US Adults

JAMA Health Forum
This cross-sectional study uses data from a nationally representative survey to evaluate the proportion of US adults who know someone who died of a drug overdose and whether this experience is associated with viewing addiction as an important policy ...
Alene Kennedy-Hendricks, Catherine K. Ettman, Sarah E. Gollust, Sachini Bandara, S. Abdalla, Brian C. Castrucci, Sandro Galea   +6 more
semanticscholar   +1 more source

Changes in characteristics of drug overdose death trends during the COVID-19 pandemic

The International journal on drug policy, 2021
Background Reports analyzing drug overdose (OD) mortality data during the COVID-19 pandemic are limited. Outcomes across states are heterogenous, necessitating assessments of associations between COVID-19 and OD deaths on a state-by-state level.
C. DiGennaro, Gian-Gabriel P. Garcia, E. Stringfellow, S. Wakeman, M. Jalali   +4 more
semanticscholar   +1 more source