Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz +9 more
wiley +1 more source
FDA Regulation of Electronic Nicotine Delivery Systems and the “Deeming” Rule: What’s Left for States? [PDF]
Hoke, Kathleen +2 more
core +1 more source
‘It’s not like they’re selling drugs over the counter’: a qualitative exploration of non-athlete perceptions of the risks, regulations and packaging attributes on sports foods in Australia [PDF]
Celeste I. Chapple +3 more
openalex +1 more source
A study on the evaluation of drug package inserts: a prospective observational study
Anita Yuwnate, Ananya Chakravorty
openalex +2 more sources
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan +6 more
wiley +1 more source
Sustainable bioplastics manufacturing from renewable sources. [PDF]
Giosafatto CVL +6 more
europepmc +1 more source
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
Nonswallowed Kratom-Derived Products: Unlawful Dietary Supplements That Endanger Public Health. [PDF]
White CM +3 more
europepmc +1 more source
Industrial Employers and Distributors Association and International Longshore and Warehouse Union (ILWU), International Brotherhood of Teamsters (IBT), Locals 6 and 17 (2003) [PDF]
core +1 more source
Package of interventions for harm reduction among women who inject drugs in Nigeria [PDF]
Aisha Dadi +6 more
openalex +1 more source

