Results 201 to 210 of about 4,880,703 (380)

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Application of Orthoflavivirus Pseudovirus Technology in Antiviral Research. [PDF]

Int J Mol Sci
Zhang Y, Zhao Y, Wang C, Zhou Y, Yuan H, Li X, Wang Y, Pan X.   +7 more
europepmc   +1 more source

ANALYSIS OF PACKAGE INSERTS OF ANTIMICROBIAL DRUGS UTILISED IN A TERTIARY CARE HOSPITAL OF NORTH KARNATAKA

, 2023
ANAND M INGALE, PRIYANKA S. PALABHAVI
openalex   +2 more sources

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

Plant-Based Polysaccharide Gums as Sustainable Bio-Polymers: Focus on Tragacanth Gum and Its Emerging Applications. [PDF]

Polymers (Basel)
Dogra S, Yadav D, Koul B, Rabbee MF.
europepmc   +1 more source

Packaging challenge for COVID-19 drug [PDF]

, 2020
Chand Anupam
openalex   +1 more source

Package insertsof antirheumatic and antiarthritic drugs [PDF]

Arthritis & Rheumatism, 1981
openaire   +2 more sources

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Sustainable Solutions for Eye Drop Plastic Waste: Challenges, Innovations, and Environmental Impact. [PDF]

J Ophthalmol
Gandhi S, Balas M, Rai A.
europepmc   +1 more source

Research on Inclusive Design Strategies for Packaging of OTC Drugs for the Elderly [PDF]

Kun Huang
openalex   +1 more source