Results 181 to 190 of about 6,763,509 (345)

Stagnation in the Drug Development Process: Are Patents the Problem? [PDF]

The rate of new drug development has stagnated, in spite of large increases in both private and public sector spending on biomedical research. The flip side of slower progress is higher drug costs.
Dean Baker
core  

Dysregulation of the MACF1‐Rab14/KIF16B‐FGFR Vesicular Trafficking Axis Skews MSC Lineage Commitment in Glucocorticoid‐Induced Osteoporosis

Advanced Science, EarlyView.
Under normal conditions, MACF1 interacts with Rab14 and facilitates KIF16B‐mediated FGFR vesicle trafficking along microtubules to the plasma membrane, thereby supporting BMSC differentiation. In contrast, chronic GC exposure suppresses MACF1 expression, disrupting this transport and causing intracellular FGFR retention, which blunts osteogenic ...
Peihong Su, Ye Tian, Fan Zhao, Jing Li, Suryaji Patil, Chunyu Zhu, Yujia Tian, Junrong Wang, Jiating Liu, Aoqi Xiang, Hua Guan, Lusha Zhang, Xiaochang Chen, Airong Qian, Qi Yu   +14 more
wiley   +1 more source

Correction: Antipsychotic Drug Prescriptions for Transition-Age Youth on the Autism Spectrum. [PDF]

J Autism Dev Disord
Benevides TW, Rast J, Lee B, Anderson K, Ventimiglia J, Jaremski JE, Poon J, Brodkin ES, Shea L.   +8 more
europepmc   +1 more source

Interstitial lung disease in rheumatoid arthritis: incidence, prevalence and related drug prescriptions between 2007 and 2020. [PDF]

RMD Open, 2023
Albrecht K, Strangfeld A, Marschall U, Callhoff J.   +3 more
europepmc   +1 more source

Electronic Chip‐Mimetic Medical Implants for Controllable Sonothermal Treatments

Advanced Science, EarlyView.
Inspired by the thermal effect of working electronic chips, which consist of various heterostructures, an sonothermal‐responsive platform has been developed through constructing metal‐semiconductor interface on implants. Biofilm infection and deep vein thrombosis can be successfully treated by controllable ultrasound treatments.
Zhengdong Zhang, Pan Liu, Jie Lei, Shuchang Peng, Qiu Chen, Wei Guan, Yizhou Zhu, Gang Liu, Xiaobo Feng, Cao Yang, Lei Tan   +10 more
wiley   +1 more source

Application research of learning curve in the training of pharmacists for the review of narcotic and psychotropic drug prescriptions. [PDF]

Front Med (Lausanne)
Xu J, Xu M, Wang X, Ren H, Luo J, Xi H, He Q.   +6 more
europepmc   +1 more source

The incidence and risk factors of selected drug prescriptions and outpatient care after SARS-CoV-2 infection in low-risk subjects: a multicenter population-based cohort study. [PDF]

Front Public Health, 2023
Gagliotti C, Banchelli F, De Paoli A, Buttazzi R, Narne E, Ricchizzi E, Schievano E, Bellio S, Pitter G, Tonon M, Canziani LM, Rolli M, Tacconelli E, Berti E, Russo F, Moro ML.   +15 more
europepmc   +1 more source

Off-label prescriptions in intensive care unit: the Chinese experience

, 2018
Lin Liu, Hong-Yu Yang, Yan Lou, Jing Miao, Xiao-Yang Lu, Qing-Wei Zhao, Rong-Rong Wang, Sai-Ping Jiang,* Xing-Guo Zhang* Department of Pharmacy, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, People’s Republic ...
Yang H, Liu L, Lu X, Wang R, Zhao Q, Zhang X, Lou Y, Jiang S, Miao J   +8 more
core  

Discrete 2D Material Programming for 3D Shaping and Morphogenesis‐Inspired 4D Bioprinting

Advanced Science, EarlyView.
Cell‐compatible discrete 2D material programming enables 2‐to‐3D shape transformation and morphogenesis‐inspired 4D bioprinting. By patterning cell‐supportive microdomains within a responsive hydrogel, the approach programs in‐plane growth to encode target metrics.
Fereshteh Family, Aneela Davuluri, Athulya Martin, Kyungsuk Yum   +3 more
wiley   +1 more source

Editorial Note: Drug prescriptions preceding opioid-related deaths-a register study in forensic autopsy patients. [PDF]

PLoS One
PLOS One Editors.
europepmc   +1 more source