Dysregulated Tissue resident macrophage (TRMs) link to autoimmune inflammation. SMURF2 mediates Lys‐27 (K27)‐linked ubiquitination of p‐TBK1 and its degradation, which inhibits CSF1R signaling‐triggered TRM proliferation, thereby restraining the autoimmune inflammation.
Xiang An +8 more
wiley +1 more source
Trends in Benzodiazepine and Z-Drug Prescriptions in Eastern China (2015-2021). [PDF]
Deng Q, Chen H.
europepmc +1 more source
Drug Prescriptions among Italian and Immigrant Pregnant Women Resident in Italy: A Cross-Sectional Population-Based Study. [PDF]
D'Aloja P +8 more
europepmc +1 more source
RA of EEAR inhibits TGF‐β1 ubiquitination and changes conformation by target binding TGF‐β1, regulating TGF‐β1/Smad2/3 signaling pathway. Thus it down‐regulated downstream protein expression, inhibited EMT and collagen deposition of ECM, in order to EEAR preventing PF in COPD.
Lingfeng Peng +6 more
wiley +1 more source
Investigating racial disparities in drug prescriptions for patients with endometriosis. [PDF]
Kashyap A +5 more
europepmc +1 more source
Kidney Disease Management in the Hospital Setting: A Focus on Inappropriate Drug Prescriptions in Older Patients. [PDF]
Arcoraci V +9 more
europepmc +1 more source
Role of Dentists in Prescribing Opioid Analgesics and Antibiotics: An Overview [PDF]
Ackerman +99 more
core +2 more sources
Prescription for Poverty: Drug companies as tax dodgers, price gougers, and influence peddlers [PDF]
Mark Fried
openalex +1 more source
Metformin Impairs Breast Cancer Growth through the Inhibition of PRMT6
Metformin has a biological activity against breast cancer. However, it is largely unknown about its precise therapeutic targets. Here, histone arginine methyltransferase PRMT6 is identified as a new anti‐cancer target for metformin. Metformin directly binds PRMT6 and inhibits its ability to catalyze histone H3R2 asymmetric dimethylation (H3R2me2a ...
Yinsheng Wu +9 more
wiley +1 more source
Physicians' information-seeking, appraising, and clinical decision-making practices for drug prescriptions: an exploratory study. [PDF]
Nath A, Meyer J, Templier M.
europepmc +1 more source

