Results 51 to 60 of about 1,839,920 (311)
Journal of Infection and Public Health, 2012 Summary: Bacterial resistance to antimicrobial agents is increasing. Complex resistant mechanisms have resulted in a wide spectrum of species and strains with multidrug-resistant patterns.
Rima I. El-Herte +3 more
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Propagandas de medicamentos em revistas femininas
Saúde em DebateEste artigo tem como objetivo analisar as propagandas de medicamentos veiculadas em revistas femininas de circulação nacional, conforme a RDC 102/00.
Marselle Nobre de Carvalho +1 more
doaj +2 more sources
Public health and international drug policy [PDF]
The Lancet, 2016 In September, 2015, the member states of the UN endorsed Sustainable Development Goals (SDGs) for 2030, which aspire to human-rights-centred approaches to ensuring the health and wellbeing of all people. The SDGs embody both the UN Charter values of rights and justice for all and the responsibility of states to rely on the best scientific evidence as ...
Csete, Joanne +25 more
openaire +3 more sources
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
, 2020 Approximately one third of newly discovered drug molecules show insufficient water solubility and therefore low oral bio-availability. Self-nano-emulsifying drug-delivery systems (SNEDDSs) are one of the emerging strategies developed to tackle the issues
Beloqui Garcia, Ana +7 more
core +1 more source
Drug shortage: a public health problem [PDF]
Cadernos de Saúde Pública, 2016 that has increased in Brazil in the last decade, interfer-ing in all levels of care, both public and private, from primary to specialized care. As a complex and multifactorial phenomenon, it is influ-enced by elements of pharmaceutical logistics and diverse political factors, from broad defini-tions for the health and science and technology sectors to ...
Mário Borges Rosa +2 more
openaire +3 more sources
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Revista Vasca de Administración Pública, 2017 This study aims to discuss the risks and benefits of direct-toconsumer advertising of drugs and prescription drugs. The general objetive of the regulation in the European Union is to protect the rational use of drugs , and impose on Member States a ban ...
M.ª Asunción Torres López
doaj +1 more source