Results 31 to 40 of about 1,787,106 (336)

Association between HLA-B Alleles and Carbamazepine-Induced Maculopapular Exanthema and Severe Cutaneous Reactions in Thai Patients

Journal of Immunology Research, 2018
The HLA-B∗15:02 allele has been reported to have a strong association with carbamazepine-induced Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) in Thai patients.
Chonlaphat Sukasem, Chonlawat Chaichan, Thapanat Nakkrut, Patompong Satapornpong, Kanoot Jaruthamsophon, Thawinee Jantararoungtong, Napatrupron Koomdee, Suthida Sririttha, Sadeep Medhasi, Sarawut Oo-Puthinan, Ticha Rerkpattanapipat, Jettanong Klaewsongkram, Pawinee Rerknimitr, Papapit Tuchinda, Leena Chularojanamontri, Napatra Tovanabutra, Apichaya Puangpetch, Wichai Aekplakorn   +17 more
doaj   +1 more source

Idiopathic non-histaminergic acquired angioedema: a case series and discussion of published clinical trials

Clinical and Translational Allergy, 2017
Background Idiopathic non-histaminergic acquired angioedema (InH-AAE) is a rare disease for which there are no available laboratory parameters to clearly define the disorder. Therapy is often difficult and various treatment options have been proposed. In
Martin Christian Bucher, Tatjana Petkovic, Arthur Helbling, Urs Christian Steiner   +3 more
doaj   +1 more source

Analgesic and Hepatoprotective Activity of Methanolic Leaf Extract of Ocimum gratissimum (L.). [PDF]

, 2012
The methanolic extract of Ocimum gratissimum (L.) leaves was screened for analgesic and hepatoprotective activity in albino rats, respectively. The use of the hot-plate method to study central analgesic activity of the leaves extract in albino rats ...
Akubugwo, E. I., Chinyere, Godwin C, Elekwa, Ifeanyi, Iweala, E. E. J., Uhegbu, Friday O.   +4 more
core   +1 more source

DRESS Syndrome: An Unusual Side Effect [PDF]

Journal of Clinical and Diagnostic Research, 2019
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) syndrome is often an overlooked entity manifesting as fatal hypersensitivity response associated with use of aromatic anti-epileptic drugs.
Kapil Bhalla, Sanjiv Nanda, Ashish Gupta, Deepak Nehra, Shuchi Mehra   +4 more
doaj   +1 more source

DRESS: características clinicopatológicas em 10 casos de Hospital Universitário em São Paulo [PDF]

, 2012
BACKGROUND: Drug reaction with eosinophilia and systemic symptoms is a severe form of drug-induced reaction with multiorgan involvement. OBJECTIVES: The aim of this study is to evaluate the epidemiological, clinical and pathological features and ...
Botelho, Luciane Francisca Fernandes, Enokihara, Mílvia Maria Simões e Silva, Higashi, Viviane Shinsato, Padilha, Maria Helena Valle de Queiroz, Porro, Adriana Maria   +4 more
core   +4 more sources

Single-Center Clinico-Pathological Case Study of 19 Patients with Cutaneous Adverse Reactions Following COVID-19 Vaccines

Dermatopathology, 2021
(1) Background: Coronavirus disease 2019 (COVID-19) vaccines are currently employed on a population-wide scale in most countries worldwide. Data about unusual cutaneous adverse drug reactions (ADR) are scant, though.
Dennis Niebel, Joerg Wenzel, Dagmar Wilsmann-Theis, Jana Ziob, Jasmin Wilhelmi, Christine Braegelmann   +5 more
doaj   +1 more source

Facile one-pot synthesis of amoxicillin-coated gold nanoparticles and their antimicrobial activity [PDF]

, 2014
Nanomaterials have been the object of intense study due to promising applications in a number of different disciplines. In particular, medicine and biology have seen the potential of these novel materials with their nanoscale properties for use in ...
A Fleming, A Kumar, A Rai, B Duncan, CK Kim, D Pissuwan, E Boisselier, G Frens, H Gu, HC Neu, J Turkevich, JD Gibson, KB Holten, M Brust, M De, MC Daniel, MN Martin, P Ghosh, RA Sperling, V Sambhy   +19 more
core   +1 more source

Adverse Drug Reaction Classification With Deep Neural Networks [PDF]

, 2016
We study the problem of detecting sentences describing adverse drug reactions (ADRs) and frame the problem as binary classification. We investigate different neural network (NN) architectures for ADR classification.
He, Yulan, Huynh, Trung, Rüger, Stefan, Willis, Alistair   +3 more
core   +1 more source

Poly (glycerol adipate) (PGA), an enzymatically synthesized functionalizable polyester and versatile drug delivery carrier : A literature update [PDF]

, 2019
The enzymatically synthesized poly (glycerol adipate) (PGA) has demonstrated all the desirable key properties required from a performing biomaterial to be considered a versatile "polymeric-tool" in the broad field of drug delivery.
Garnett, Martin C., Styliari, Ioanna Danai, Swainson, Sadie M.E., Taresco, Vincenzo   +3 more
core   +3 more sources

FoxO1 signaling in B cell malignancies and its therapeutic targeting

FEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac, Petra Pavelkova, Laura Ondrisova, Marek Mraz   +3 more
wiley   +1 more source