Results 81 to 90 of about 9,770,479 (402)
Objective Social media is becoming increasingly popular as a platform for sharing personal health-related information. This information can be utilized for public health monitoring tasks, particularly for pharmacovigilance, via the use of natural ...
Azadeh Nikfarjam +4 more
semanticscholar +1 more source
A four-month gatifloxacin-containing regimen for treating tuberculosis. [PDF]
BACKGROUND: Shortening the course of treatment for tuberculosis would be a major improvement for case management and disease control. This phase 3 trial assessed the efficacy and safety of a 4-month gatifloxacin-containing regimen for treating rifampin ...
Amukoye, Evans +19 more
core +1 more source
Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer +10 more
wiley +1 more source
Amiodarone is an effective medication used in the treatment of several different arrhythmias. Its most well-known adverse effects include pulmonary fibrosis, thyroid dysfunction, and hepatotoxicity. A less common side effect is acute pancreatitis.
Christopher J. Mercogliano +2 more
doaj +1 more source
The use of drug calendars for the diagnosis of cutaneous drug eruptions in the age of electronic medical records [PDF]
A morbilliform drug eruption is the most common condition leading to a dermatology consultation for a patient in the hospital. Timing is an important diagnostic tool since the onset of a skin rash usually takes place within days-to-weeks of the start of ...
Cohen, Philip R, Grossman, Marc E
core
Insights into DNA platination within unusual structural settings [PDF]
2D [1H, 15N] HSQC NMR spectroscopy has been used to monitor reaction and product formation between [Pt(15NH3)2I2] and nucleic acids possessing irregular topologies and containing site specific phosphorothioate substitution in the phosphodiester backbone.
Harvie, Stephanie +2 more
core +2 more sources
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican +7 more
wiley +1 more source
Drug delivery systems - Winter school on recent advances in diagnosis and management of diseases in mariculture, 7th to 27th November 2002, Course Manual [PDF]
Drug delivery systems are designed based on the action of the drug in the body, reaction of the body to these drugs and the active drug available in the body for therapeutic action.
Gopakumar, N
core
Novel and unscrutinized immune entities of the zebrafish gut
Understudied cells of the zebrafish immune system include bona fide immune cells and epithelial (‐derived) cells with immune functions. Research focusing on zebrafish cells which demonstrate similarities to mammalian immune cell counterparts may help us understand the pathologies in which they are implicated. Currently available and advanced tools make
Audrey Inge Schytz Andersen‐Civil +5 more
wiley +1 more source
Striking enhancement at the site of radiation for nivolumab-induced Stevens-Johnson syndrome [PDF]
Stevens-Johnson syndrome is a rare adverse cutaneous drug reaction characterized by epidermal detachment of
Al-Omari, Ahmed +2 more
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