Results 41 to 50 of about 14,448,012 (256)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Identification of drug-related problems and pharmacist′s interventions in asthmatic patients at a private tertiary care facility-Pakistan

Archives of Pharmacy Practice, 2015
Background: Drug-related problems (DRPs) potentially contribute to morbidity, mortality and financial indicators. There is increasing evidence that participation and interventions of clinical pharmacists in health care have a positive influence on ...
Aziz Ullah Khan, Iftikhar Ali, Roheena Zafar, Abdul Khalil   +3 more
doaj   +1 more source

Drug-Related Problems in Pulmonary Hypertension with Valvular Heart Disease

, 2022
Farizan Abdul-Ghaffar,1,2 Adyani Md Redzuan,1 Mohd Makmor-Bakry,1 Mohamad Arif Muhamad Nor3 1Faculty of Pharmacy, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia; 2Department of Pharmacy, Hospital Serdang, Kajang, Malaysia; 3Department of ...
Md Redzuan A, Makmor-Bakry M, Muhamad Nor MA, Abdul-Ghaffar F   +3 more
core  

Ecstasy/MDMA attributed problems reported by novice, moderate and heavy recreational users [PDF]

, 2002
The recreational use of MDMA/Ecstasy (3,4-methylenedioxymethamphetamine) is associated with many psychobiological problems, but there is a paucity of data on how these relate to the level of past use.
Buchanan, Tom, Scholey, Andrew, Parrott, A.C., Heffernan, T., Ling, J., Heffernan, Tom, Parrott, Andrew, Scholey, A.B., Rodgers, J., Ling, Jonathan, Rodgers, Jacqui, Buchanan, T.   +11 more
core   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Drug-related problems (DRPs) identified from geriatric medication safety review clinics

, 2014
Drug-related problems (DRPs) were identified from baseline data of 193 Medication Safety Review Clinic (MSRC) patients. MSRCs enroll older adults (>= 65 years) with either (1) prescriptions of >= 8 chronic medications (drugs prescribed for >= 28
Chan, Ding-Cheng;Chen, Jen-Hau;Kuo, Hsu-Ko;We, Chiung-Jung;Lu, I-Shu;Chiu, Lee-Shu;Wu, Shwu-Chong, 詹鼎正 ;吳淑瓊 ;陳人豪 ;呂奕樞   +1 more
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Drug-related deaths in Scotland in 2020. [PDF]

, 2021
Statistics of drug-related deaths, broken down by age, sex, substances implicated in the death, underlying cause of death, and NHS Board and Council areas.

core  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Minding the gap. Drug-related problems among breastfeeding women

Frontiers in Pharmacology
IntroductionDrug-related problems (DRPs) are a significant concern in many patient populations, including breastfeeding women. This study aimed to identify and characterize those problems in a group of breastfeeding women seeking specialized ...
Karolina Morze, Edyta Szałek, Magdalena Waszyk-Nowaczyk   +2 more
doaj   +1 more source