Results 51 to 60 of about 15,916,923 (301)
Drug-related problems (DRPs) identified from geriatric medication safety review clinics
, 2014 Drug-related problems (DRPs) were identified from baseline data of 193 Medication Safety Review Clinic (MSRC) patients. MSRCs enroll older adults (>= 65 years) with either (1) prescriptions of >= 8 chronic medications (drugs prescribed for >= 28
Chan, Ding-Cheng;Chen, Jen-Hau;Kuo, Hsu-Ko;We, Chiung-Jung;Lu, I-Shu;Chiu, Lee-Shu;Wu, Shwu-Chong +1 more
core +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Supports needed for Irish families mourning drug-related deaths.
, 2022 Opinion: families who lose a loved one to a drug death experience a silent grief that puts them at risk of intense mental and physical health problems..
O'Callaghan, Daniel, Lambert, Sharon
core
The multifaceted roles of lysosomes in cancer
Molecular Oncology, EarlyView.Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley +1 more source
Drug related problems in older adults living with dementia.
PLoS ONE, 2020 BackgroundCompared with those without dementia, older patients with dementia admitted to acute care settings are at higher risk for triad combination of polypharmacy (PP), potentially inappropriate medication (PIM), and drug-drug interaction (DDI), which
Sirasa Ruangritchankul +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi +2 more
wiley +1 more source
Acute health problems due to recreational drug use in patients presenting to an urban emergency department in Switzerland [PDF]
, 2015 QUESTIONS UNDER STUDY: To describe acute toxicity of recreational drugs including novel psychoactive substances. METHODS: We included all cases presenting at the emergency department (ED) of the University Hospital of Basel, Switzerland, between ...
Dolder, Patrick C. +13 more
core +2 more sources
Archives of EpilepsyObjective: Interventions by clinical pharmacists are required to identify and resolve medication-related problems. This study aimed to identify drug-related problems (DRPs) encountered by patients with epilepsy, provide pharmaceutical care (PC ...
Unyime Eshiet +2 more
doaj +1 more source
Protocol for quantifying miRNA trafficking across the endosomal membrane
FEBS Open Bio, EarlyView.An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source
Pharmacist interventions for older adults with polypharmacy in an ambulatory geriatric clinic
Health Literacy and Communication OpenIntroduction Polypharmacy is a concern among older adults. An academic medical center in northeast Ohio currently has an outpatient geriatric medicine clinic with an embedded board-certified geriatric pharmacist who performs comprehensive medication ...
Antonietta Paneccasio +6 more
doaj +1 more source