Results 61 to 70 of about 14,448,012 (256)
FEBS Open Bio, EarlyView.Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar +4 more
wiley +1 more source
Patient involvement is essential in identifying drug‐related problems [PDF]
British Journal of Clinical Pharmacology, 2018 AimsThe aim of this study is to evaluate how critical patient involvement is in pharmacist‐led clinical medication reviews and in identifying the most significant clinical drug‐related problems (DRPs).MethodsPharmacist‐led clinical medication reviews were conducted with 161 consenting patients aged ≥75 years with at least seven prescribed medicines ...
Heini Kari +3 more
openaire +2 more sources
Protocol for quantifying miRNA trafficking across the endosomal membrane
FEBS Open Bio, EarlyView.An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source
Alcohol‐ and drug‐related absenteeism: a costly problem
Australian and New Zealand Journal of Public Health, 2016 Absenteeism related to alcohol and other drug (AOD) use can place a substantial burden on businesses and society. This study estimated the cost of AOD-related absenteeism in Australia using a nationally representative dataset.A secondary analysis of the 2013 National Drug Strategy Household Survey (n=12,196) was undertaken.
Ann Roche, Ken Pidd, Victoria Kostadinov
openaire +3 more sources
Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank
FEBS Open Bio, EarlyView.Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer +7 more
wiley +1 more source
Nordic Studies on Alcohol and Drugs, 2014 AIMS – To study the prevalence of cannabis use and drug-related problems among European adolescents and the utility of the prevention paradox. METHODS – Survey data from the European School Survey Project on Alcohol and Other Drugs (ESPAD) in 2007 in the
Romelsjö Anders +3 more
doaj +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Critical Contribution of Pharmacists in Optimising Medication Safety among Children: A Narrative Review [PDF]
Journal of Clinical and Diagnostic ResearchPaediatric patients are particularly vulnerable to medication errors and Adverse Drug Reactions (ADRs), with the incidence of adverse drug events being three times higher in children compared to adults.
Pulkit Deswal +2 more
doaj +1 more source
Supports needed for Irish families mourning drug-related deaths.
, 2022 Opinion: families who lose a loved one to a drug death experience a silent grief that puts them at risk of intense mental and physical health problems..
O'Callaghan, Daniel, Lambert, Sharon
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Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Cognitive impairment is a common non‐motor symptom in Multiple Sclerosis (MS), negatively affecting autonomy and Quality of Life (QoL). Innovative rehabilitation strategies, such as semi‐immersive virtual reality (VR) and computerized cognitive training (CCT), may offer advantages over traditional cognitive rehabilitation (TCR ...
Maria Grazia Maggio +8 more
wiley +1 more source