Results 11 to 20 of about 915,020 (267)
Journal of Nanobiotechnology, 2021 Bacterial biofilm is the complicated clinical issues, which usually results in bacterial resistance and reduce the therapeutic efficacy of antibiotics.
Xiangjun Chen +6 more
doaj +1 more source
Journal of Nanobiotechnology, 2021 Background Biofilm formation is one of the main reasons for persistent bacterial infections. Recently, pH-sensitive copolymers have fascinated incredible attention to tackle biofilm-related infections.
Rong Guo +7 more
doaj +1 more source
Modular assembly of indole alkaloids enabled by multicomponent reaction
Nature Communications, 2023 Indole alkaloids are one of the largest alkaloid classes, proving valuable structural moiety in pharmaceuticals. Although methods for the synthesis of indole alkaloids are constantly explored, the direct single-step synthesis of these chemical entities ...
Jiaming Li +4 more
doaj +1 more source
Molecules, 2023 In this study, a collection of newly developed α-methylchalcone derivatives were synthesized and assessed for their inhibitory potential against human cervical cancer cell lines (HeLa, SiHa, and C33A) as well as normal human cervical epithelial cells (H8)
Zheng Yang +5 more
doaj +1 more source
Nano Composite Fe-Co-V /Zeolite as a Nano Carrier for Folic Acid Drug Controlled Release [PDF]
Trends in Pharmaceutical Sciences, 2021 large reserves of zeolites has been one of the comparative advantages of the country in this field and provides economic justification for its use in a variety of applications, including medical and pharmaceutical fields such as artificial kidney ...
Shima Zangeneh Yousef Abadi +2 more
doaj +1 more source
Hydrogel-Based Microneedle as a Drug Delivery System
Pharmaceutics, 2023 The skin is considered the largest and most accessible organ in the human body, and allows the use of noninvasive and efficient strategies for drug administration, such as the transdermal drug delivery system (TDDS).
David Filho +4 more
doaj +1 more source
Controlled Drug Release Asymptotics [PDF]
SIAM Journal on Applied Mathematics, 1998 This paper deals with the solution of Higushi's model for controlled release of drugs when the solubility of the drug in the polymer matrix is a prescribed function of time. The model is described as a one-phase moving boundary problem which cannot be solved exactly. Two limits of the problem are considered.
Cohen, Donald S., Erneux, Thomas
openaire +2 more sources
A Transformer-Based Ensemble Framework for the Prediction of Protein–Protein Interaction Sites
Research, 2023 The identification of protein–protein interaction (PPI) sites is essential in the research of protein function and the discovery of new drugs. So far, a variety of computational tools based on machine learning have been developed to accelerate the ...
Minjie Mou +8 more
doaj +1 more source
Polyglycolide: Degradation and drug release. Part II: Drug release
Journal of Materials Science: Materials in Medicine, 2001 This paper considers drug release from a polyglycolide (PGA) matrix and is divided into two sections. The first investigates the effects on the degradation of the polymer of incorporating a model drug, theophylline, into the polymer. Small and wide angle X-ray scattering, and mass loss and water uptake measurements indicate that the presence of this ...
S, Hurrell, R E, Cameron
openaire +2 more sources
Delaying Drug Release: A Time Capsule for the Heart. [PDF]
JACC Basic Transl SciLi Y, Cheng K.
europepmc +2 more sources