Results 11 to 20 of about 3,939,397 (309)
Evaluation of drug release kinetics from ibuprofen matrix tablets using HPMC. [PDF]
, 2006 The aim of this study is to develop a once-daily sustained release matrix tablet of ibuprofen using hydroxypropyl methylcellulose (HPMC) as release controlling factor and to evaluate drug release parameters as per various release kinetic models. In order
Tazeen, Jaweria +3 more
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Controlled Drug Release Asymptotics [PDF]
SIAM Journal on Applied Mathematics, 1998 This paper deals with the solution of Higushi's model for controlled release of drugs when the solubility of the drug in the polymer matrix is a prescribed function of time. The model is described as a one-phase moving boundary problem which cannot be solved exactly. Two limits of the problem are considered.
Cohen, Donald S., Erneux, Thomas
openaire +4 more sources
Controlled Drug Release from Nanoengineered Polysaccharides
, 2023 Polysaccharides are naturally occurring complex molecules with exceptional physicochemical properties and bioactivities. They originate from plant, animal, and microbial-based resources and processes and can be chemically modified.
Ilker S. Bayer
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Polyglycolide: Degradation and drug release. Part II: Drug release
Journal of Materials Science: Materials in Medicine, 2001 This paper considers drug release from a polyglycolide (PGA) matrix and is divided into two sections. The first investigates the effects on the degradation of the polymer of incorporating a model drug, theophylline, into the polymer. Small and wide angle X-ray scattering, and mass loss and water uptake measurements indicate that the presence of this ...
S, Hurrell, R E, Cameron
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Tablet Geometry Effect on the Drug Release Profile from a Hydrogel-Based Drug Delivery System
, 2023 In order to achieve the optimal level of effectiveness and safety of drugs, it is necessary to control the drug release rate. Therefore, it is important to discover the factors affecting release profile from a drug delivery system.
Majid Baniassadi +4 more
core +1 more source
Kinetics of Drug Release from Clay Using Enhanced Sampling Methods
, 2022 A key step in the development of a new drug, is the design of drug–excipient complexes that lead to optimal drug release kinetics. Computational chemistry and specifically enhanced sampling molecular dynamics methods can play a key role in this ...
Parrinello, Michele +5 more
core +1 more source
Modulation of Drug Release in Anticancer Therapy: Recent Advances, Challenges, and Emerging Drug Delivery Platforms. [PDF]
PharmaceuticsAchieving precise control over anticancer drug release remains one of the key challenges in modern pharmaceutical development, as it directly determines therapeutic efficacy, systemic toxicity, and patient outcomes.
Sokač Pogrmilović K +2 more
europepmc +2 more sources
The Role of Oral Controlled Release Matrix Tablets in Drug Delivery Systems [PDF]
, 2012 Formulations that are able to control the release of drug have become an integral part of the pharmaceutical industry. In particular oral drug delivery has been the focus of pharmaceutical research for many years.
Raja, Shaista +11 more
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On the Heterogeneity of Drug Dissolution and Release
Pharmaceutical Research, 2000 release. We re-interpreted, in terms of the heterogeneity of the reaction and/or diffusion space topology, the conventional Eq. 3 has a classical exponential form concaving downwards parameters of the current models using experimental data from throughout the time course of the process approaching the in vitro studies.
Macheras, P., Dokoumetzidis, A.
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Breath-Triggered Drug Release System for Preterm Neonates
, 2021 A major disadvantage of inhalation therapy with continuous drug delivery is the loss of medication during expiration. Developing a breath-triggered drug release system can highly decrease this loss.
Fabian Müller +5 more
core +1 more source