Results 181 to 190 of about 26,660 (305)

How Can Pharmacology Help Us Overcome the Challenges of Drug Repositioning as Antivirals to Treat Emerging Pathogens? The Example of Covid-19. [PDF]

Clin Transl Sci
Ben Ghezala I, Peiffer-Smadja N, Solas C, Nougairède A, Touret F, Bardou M.   +5 more
europepmc   +1 more source

CBMS-12 PENTAMIDINE; TRANSLATIONAL RESEARCH FOR A NEW CHEMOTHERAPY TARGETING ON GLIOMA CELLS AND GLIOMA STEM CELLS USING DRUG REPOSITIONING [PDF]

, 2019
Sho Tamai, Hemragul Sabit, Shabierjiang Jiapaer, Guangtao Zhang, Jiakang Zhang, Yi Wang, Shingo Tanaka, Masashi Kinoshita, Atsushi Hirao, Mitsutoshi Nakada   +9 more
openalex   +1 more source

Long‐Term Results of UPPP and Coblation Channeling of the Tongue for Obstructive Sleep Apnea

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective To evaluate the long‐term surgical outcomes of combined uvulopalatopharyngoplasty (UPPP) and coblation channeling of the tongue (CCT) for moderate‐to‐severe obstructive sleep apnea (OSA). Methods The study enrolled patients with moderate‐to‐severe OSA who underwent treatment with UPPP plus CCT and had a minimal follow‐up of 2 years ...
Ren‐Hui Chen, Qian Cai, Wei‐Qi Chen, Xiao‐Ming Huang   +3 more
wiley   +1 more source

Dual-route embedding-aware graph neural networks for drug repositioning. [PDF]

Brief Bioinform
Zhao Y, Chen Y, Du J, Wen J, Sun Q, Wang R, Chen C.   +6 more
europepmc   +1 more source

Epiglottis Collapse in Individuals With Obstructive Sleep Apnea

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective Obstructive sleep apnea (OSA) is a common sleep disorder characterized by repeated upper airway collapse during sleep. The epiglottis, often overlooked in conventional assessments, has emerged as a site of significant obstruction in OSA.
Dan Chen, Li Zhou, Qi‐Ying Zeng, Yu‐Yin Liu, Jia‐Jing Yang, Rui Liu, Zhi‐Hang Zhou, Fei‐Fei Chen, Li Tang, Fang‐Qi Liang, Hong‐Liang Yi, Su‐Ru Liu   +11 more
wiley   +1 more source

Chinese Guidelines for the Diagnosis and Surgical Treatment of Adult Obstructive Sleep Apnea (2024)

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Obstructive sleep apnea (OSA) is a common chronic disorder characterized by abnormal breathing during sleeping. OSA can damage various organs throughout the body and is burdensome, both socially and economically. Moreover, as OSA has been increasingly studied in recent years, new evidence‐based guidelines for its diagnosis and surgical ...
Working Group of Guideline for the Diagnosis and Surgical Treatment of Adult OSA, Subspecialty Group of Laryngopharyngology, Society of Otorhinolaryngology Head and Neck Surgery, Chinese Medical Association, Subspecialty Group of Voice, Society of Otorhinolaryngology Head and Neck Surgery, Chinese Medical Association, Editorial Board of Chinese Journal of Otorhinolaryngology Head and Neck Surgery   +7 more
wiley   +1 more source

SMPR: a structure-enhanced multimodal drug‒disease prediction model for drug repositioning and cold start. [PDF]

J Cheminform
Dong X, Miao R, Zhang S, Jia S, Zhang L, Liang Y, Zhang J, Zhu YZ.   +7 more
europepmc   +1 more source

A comparative benchmarking and evaluation framework for heterogeneous network-based drug repositioning methods [PDF]

Yinghong Li, Yinqi Yang, Zhuohao Tong, Yu Wang, Qin Mi, Mingze Bai, Guizhao Liang, Bo Li, Kunxian Shu   +8 more
openalex   +1 more source

A two-step drug repositioning method based on a protein-protein interaction network of genes shared by two diseases and the similarity of drugs [PDF]

, 2013
Yutaka Fukuoka, Daiki Takei, Hisamichi Ogawa   +2 more
openalex   +1 more source

AstroECP: towards more practical electron channeling contrast imaging

Journal of Applied Crystallography, EarlyView.
We explore and address many of the major challenges associated with using electron channeling contrast imaging in a scanning electron microscope, with the goal of more easily revealing and characterizing crystalline defects such as dislocations.Electron channeling contrast imaging (ECCI) is a scanning electron microscope based technique which enables ...
M. Haroon Qaiser, Lukas Berners, Robin J. Scales, Tianbi Zhang, Martin Heller, Jiří Dluhoš, Sandra Korte-Kerzel, T. Ben Britton   +7 more
wiley   +1 more source