Results 191 to 200 of about 82,231 (299)

Advancing Maternal Health with Long‐Acting Therapeutics: Priorities, Efficacy and Safety Considerations, and Emerging Technologies

Clinical Pharmacology &Therapeutics, EarlyView.
Maternal health remains a critical global concern, particularly in underserved populations and in low‐ and middle‐income countries where access to safe and effective therapeutics is limited. Despite the use of medications by most women during pregnancy, the exclusion of pregnant and lactating women from clinical trials has resulted in significant data ...
Rachel K. Scott, Sharon Nachman, Ethel D. Weld, Rachel Daley, Shakir Atoyebi, Robert Bies, Catriona Waitt, Adeniyi Olagunju   +7 more
wiley   +1 more source

Comic: explainable drug repurposing via contrastive masking for interpretable connections. [PDF]

BMC Bioinformatics
Aamer N, Asim MN, Dengel A.
europepmc   +1 more source

Repurposing Drugs – Repurposing Diseases

Repurposing Drugs – Repurposing Diseases
openaire   +1 more source

Advancing Pharmacoequity Globally: Reflections from the ASCPT Development, Regulatory, and Outcomes Network

Clinical Pharmacology &Therapeutics, EarlyView.
ASCPT has a mission to advance clinical pharmacology and translational sciences to reduce health disparities. The development, regulatory, and outcomes (DRO) network within ASCPT strives to advance pharmacoequity globally. Pharmacoequity, coined by Utibe Essien (2021), is the principle that all individuals, regardless of race, ethnicity, geography, or ...
Priya Jayachandran, Mayur K. Ladumor, Georgios Vlasakakis, Andrew Riselli, Katarina V. Ilic, Rob C. van Wijk, Mohamed Elmeliegy, Jatinder Kaur Mukker, Aarti Sawant‐Basak, Tao Long, Juyao Dong, Noha Rayad, Tao Zhang, on behalf of the DRO Network   +13 more
wiley   +1 more source

Drug Repurposing for Kala-Azar. [PDF]

Pharmaceutics
Arsić B, Ilić BS, Maier A, Hartung M, Janjić J, Milićević J, Baumbach J.   +6 more
europepmc   +1 more source

Safety, Pharmacokinetics, and Dose Recommendations for Nirmatrelvir/Ritonavir in Individuals with Mild to Moderate COVID‐19 and Severe Renal Impairment

Clinical Pharmacology &Therapeutics, EarlyView.
Patients with severe renal impairment and COVID‐19 are at high risk for severe disease and death. Nirmatrelvir/ritonavir, an antiviral therapy for COVID‐19, is eliminated by renal excretion and can accumulate in patients with severe renal impairment.
Jacqueline Gerhart, Candace R. Bramson, Michelle Goulding, Haihong Shi, Olayide Oladoyinbo, Phylinda L. S. Chan, Sunring Chime, Jennifer Hammond   +7 more
wiley   +1 more source

Drug repurposing in cancer research: a bibliometric analysis. [PDF]

Discov Oncol
Ndidi US, Ogra IO, Jonathan EU, Iroha OK.   +3 more
europepmc   +1 more source

Learning Strategies from Nature's Blueprint to Cyclic Carbonate Synthesis

ChemSusChem, Volume 18, Issue 6, March 15, 2025.
The development of sustainable synthetic methods for cyclic carbonates draws inspiration from nature, focusing on eco‐friendly processes and renewable resources like CO2 and biomass. This review explore various CO2 activation mechanisms, green chemistry principles, and green catalysts.
Erika Saccullo, Vincenzo Patamia, Chiara Zagni, Antonio Rescifina, Giuseppe Floresta   +4 more
wiley   +1 more source

TAS2R38 taster variants-linked MGAM expression in Alzheimer's disease: a novel target for precision drug repurposing. [PDF]

Front Aging Neurosci
Su CW, Chen K, Wu T, Reiman EM, Wang Q.
europepmc   +1 more source

High‐Performance Solar‐Thermal Hydrogel Based on Waste Biomass Materials for Power Generation and Water Purification

EcoEnergy, EarlyView.
An environmentally friendly and highly efficient solar evaporator was constructed using waste biomass materials and polyvinyl alcohol carrier, which achieves an outstanding evaporation rate of 1.48 kg m−2 h−1, corresponding to an energy conversion efficiency of 82.49% under 1.0 kW m−2 simulated sunlight irradiation.
Shuo Qi, Haiying Tian, Lu Han, Tianjiao Li, Zuoyu Wang, Pengfei Li, Yingyuan Zhang, Tao Jia, Xiuhua Zhao, Wai‐Yeung Wong, Nanxi Jin   +10 more
wiley   +1 more source