Results 171 to 180 of about 1,830,783 (287)

How Are Australian Local Governments Responding to the Homelessness Crisis? Findings From a National Study

Australian Journal of Social Issues, EarlyView.
ABSTRACT Australian local governments are facing intensifying pressures to respond to worsening visible homelessness. This paper presents one of the first national studies on how local governments are responding to these pressures, and the first since the onset of the post‐pandemic housing crisis.
Andrew Clarke, Joelle Moore, Fatemeh Aminpour, Katya Eagles   +3 more
wiley   +1 more source

Beyond Simple Mimicry: Next‐Generation Geometric Architectures and Future Paradigms in Small‐Molecule and Macrocyclic Peptidomimetics

Angewandte Chemie, EarlyView.
Peptide‐to‐Small Molecule Paradigm: Peptidomimetics have evolved from simple mimicry toward drug‐like scaffolds supported by increasing clinical successes. This Perspective highlights the geometric design principles—linear repetition, convergent fusion, and cyclization—defining the next‐generation peptidomimetic architectures capable of targeting ...
Jesang Lee, Sumin Son, Jeong Yeon Yoo, Ji Hyae Lee, Meehyun Chun, Seung Bum Park   +5 more
wiley   +2 more sources

Pharmacological Modulators of TCTP: Opportunities and Challenges for Drug Repurposing. [PDF]

Int J Mol Sci
Andrzejczyk W, Porębska K, Balasubramaniyam T, Synowiec A, Kloc M, Stączek P, Kubiak JZ.   +6 more
europepmc   +1 more source

Public Attitudes Toward Compassionate Release of Older People From Prison: Findings From a National Survey in Australia

Australian Journal of Social Issues, EarlyView.
ABSTRACT The rapid increase in older people in prison populations worldwide is generating significant health, cost, and human rights pressures on custodial systems. Compassionate release for older, frail inmates is a potentially effective response, yet little is known about public support for this approach.
Ye In (Jane) Hwang, Natasha Ginnivan, Amanuel Kidane Hagos, Tony Butler   +3 more
wiley   +1 more source

Drug Repurposing for Metabolic-Associated Fatty Liver Disease: Current Evidence, Challenges, and Future Perspectives. [PDF]

Drug Des Devel Ther
Liang X, Jin P, Xue Y, Jia Y, Zhu H, Gong G, Zhou H, Hu H, Lee SM.   +8 more
europepmc   +1 more source

Drug repurposing for bipolar disorder

, 2019
Drug repurposing for bipolar ...
M Udawela (13511989), K Bonifacio (13536379), Olivia Dean (13088112), B Panizzutti (13308942), Ken Walder (13099344), S Jamain (13517746), E Scarr (13547110), Michael Berk (13060851), Timothy Connor (13097175), Tamsyn Crowley (13097181), A Sanigorski (13279431), B Dean (8476506), Chiara Bortolasci (13060449), S Kidnapillai (13308939), M Leboyer (5536649), Briana Randall (13061973), Laura Gray (13071792)   +16 more
core  

Screening of cell-type-specific meta-programs for drug repurposing in Alzheimer's disease. [PDF]

Brief Bioinform
Zhang C, Zhang Y, Wu Z, Zhang Y, Xue F, Tan Q, Zhong X, Zhang Y, Zhao Z, Peng Y, Chen H, Li F, Zhang Y.   +12 more
europepmc   +1 more source

A drug repurposing screen reveals dopamine signaling as a candidate therapeutic pathway for PIGA-CDG. [PDF]

PLoS Genet
Aziz MC, Wilson J, Chow CY.
europepmc   +1 more source

CAREPath: semantic context-aware reasoning paths with mechanism-augmented embeddings for drug repurposing. [PDF]

Brief Bioinform
Song H, Bang D, Koo B, Kim S, Lee S.
europepmc   +1 more source

Viral Sentry AI-Automated zoonotic surveillance and drug repurposing agent. [PDF]

Biol Methods Protoc
Munteanu CR, Vázquez-Naya J, Tejera E.
europepmc   +1 more source