Results 71 to 80 of about 2,335,473 (307)

Screening Q-markers for anti-MRSA activity of Amomum tsao-ko Crevost & Lemarié essential oil based on spectrum-effect relationships

Results in Chemistry
Objective: To screen anti-MRSA Q-markers of Amomum tsao-ko essential oil (AEO) via spectrum-effect relationship, establish a quality evaluation system, and provide a scientific basis for the quality control and comprehensive utilization of AEO.
Songhao Wu, Yuwei Gu, Juan Tang, Siyi Chen, Yadan Xiao, Min Dai, Zhonghui Pu   +6 more
doaj   +1 more source

Drug targeting to tumors using HPMA copolymers [PDF]

, 2009
Copolymers based on N-(2-hydroxypropyl)methacrylamide (HPMA) are prototypic and well-characterized polymeric drug carriers that have been broadly implemented in the delivery of anticancer agents.
Dep Farmaceutische wetenschappen, Lammers, T.G.G.M., Advanced drug delivery systems/drug targeting   +2 more
core   +1 more source

Association Between Individualized Education for Kidney Replacement Therapy Modality Selection and Peritoneal Dialysis Initiation: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito, Ryuichi Yoshimura, Takaki Yamauchi, Yuta Funakoshi, Hirotaka Sonoda, Seiji Kobayashi, Hiroyuki Terawaki, Takafumi Ito   +7 more
wiley   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

BroadAMP-GPT: AI-Driven generation of broad-spectrum antimicrobial peptides for combating multidrug-resistant ESKAPE pathogens

Gut Microbes
Antimicrobial peptides (AMPs) are promising candidates to address the global antimicrobial resistance crisis, yet their traditional design remains labor-intensive and inefficient.
Yanru Li, Xianghan Xu, Xiaohui Zhang, Zhihui Xu, Jiaqi Zhao, Ruiyu Zhu, Ziyu Wang, Wei Ran, Wenqian Zhao, Ningyang Yan, Yifan Leng, Zexu Miao, Xiaomin Wang, Liping Wang, Jinxin Liu, Cong Pian, Jinhu Huang   +16 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Pharmacokinetic-pharmacodynamic integration of shikimic acid in broilers: An indirect effect modeling approach

Poultry Science
Shikimic acid (SA), a natural polyhydroxy cyclic organic acid, possesses significant anti-inflammatory and antioxidant activities; however, its pharmacokinetic (PK) profile and pharmacodynamic (PD) relationship in poultry remain poorly characterized ...
Yue Shen, Kaibin Mo, Hui Zhao, Yicheng Zhang, Xianhui Huang   +4 more
doaj   +1 more source

BALANCING FOOD SAFETY AND RISK: DO DRUG RESIDUE LIMITS AFFECT INTERNATIONAL TRADE IN BEEF? [PDF]

There have been a number of high profile food safety disputes in trade over the past decade. These include the widely publicized dispute at the World Trade Organization between the U.S. and EU over hormone treated beef.
Majumdar, Baishali, Wilson, John S., Otsuki, Tsunehiro   +2 more
core  

Brief strategic family therapy for adolescent drug abuse. [PDF]

, 2003
To ensure that treatment providers apply the most current scientifically supported approaches to their patients, NIDA has supported the development of the "Therapy Manuals for Drug Addiction" series.

core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source