Results 101 to 110 of about 377,494 (308)

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Drug Residues and Food Safety [PDF]

, 1997
Complaints and demands from consumers concerning a product usually occur after an incident involving injury, illness or death. However, this was not the case with the Alar scare with apples and it is not the case with the concern for drug residues in ...
Bagley, Clell
core   +1 more source

Engineering of a highly efficient quinone-dependent dehydrogenase for deoxynivalenol detoxification and evaluation of its in vivo protective efficacy

Ecotoxicology and Environmental Safety
To effectively address contamination caused by deoxynivalenol (DON), a strain with high DON-degrading activity was isolated from the black soldier fly larvae gut (BSFLG) and identified as Klebsiella pneumoniae BSFLG-DON15. Results showed that BSFLG-DON15
Fang Li, Chao Yang, Aqiong Gong, Wanqing Ma, Xieshi Yu, Qinghua Wu, Xu Wang   +6 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

BALANCING FOOD SAFETY AND RISK: DO DRUG RESIDUE LIMITS AFFECT INTERNATIONAL TRADE IN BEEF? [PDF]

There have been a number of high profile food safety disputes in trade over the past decade. These include the widely publicized dispute at the World Trade Organization between the U.S. and EU over hormone treated beef.
Majumdar, Baishali, Wilson, John S., Otsuki, Tsunehiro   +2 more
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Desenvolvimento e validação de método multirresíduo para determinação de resíduos de antimicrobianos em leite por CLAE-FL/DAD e CLAE-MS/MS [PDF]

, 2011
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Agrárias, Programa de Pós-Graduação em Ciência dos Alimentos, Florianópolis, 2011Antimicrobianos são extensivamente empregados na medicina veterinária para prevenção e ...
Toaldo, Isabela Maia
core  

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Quantitative Determination of Aflatoxin B₁ in Maize and Feed by ELISA and Time-Resolved Fluorescent Immunoassay Based on Monoclonal Antibodies

Foods
In this study, a highly sensitive monoclonal antibody (mAb) was developed for the detection of aflatoxin B1 (AFB1) in maize and feed. Additionally, indirect competitive enzyme-linked immunosorbent assay (ic-ELISA) and time-resolved fluorescence ...
Shiyun Han, Yalin Yang, Ting Chen, Bijia Yang, Mingyue Ding, Hao Wen, Jiaxu Xiao, Guyue Cheng, Yanfei Tao, Haihong Hao, Dapeng Peng   +10 more
doaj   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source