Results 11 to 20 of about 377,494 (308)

Recent Advances in the Determination of Veterinary Drug Residues in Food. [PDF]

open access: yesFoods, 2023
The presence of drug residues in food products has become a growing concern because of the adverse health risks and regulatory implications. Drug residues in food refer to the presence of pharmaceutical compounds or their metabolites in products such as ...
Pratiwi R   +4 more
europepmc   +2 more sources

Metabolic Disposition and Elimination of Tritum-Labeled Sulfamethoxazole in Pigs, Chickens and Rats

open access: yesMetabolites, 2022
Sulfamethoxazole (SMZ), as a sulfa antibiotic, is often used in the treatment of various infectious diseases in animal husbandry. At present, SMZ still has many unresolved problems in the material balance, metabolic pathways, and residual target tissues ...
Jingchao Guo   +10 more
doaj   +1 more source

The dose regimen formulation of doxycycline hydrochloride and florfenicol injection based on ex vivo pharmacokinetic-pharmacodynamic modeling against the Actinobacillus pleuropneumoniae in pigs

open access: yesAnimal Diseases, 2023
Doxycycline hydrochloride and florfenicol combination (DoxHcl&FF) is an effective treatment for respiratory diseases. In the study, our objective was to evaluate the activity of DoxHcl&FF against Actinobacillus pleuropneumoniae (APP) in porcine pulmonary
Yuanyuan Yuan   +8 more
doaj   +1 more source

Exploration of Clinical Breakpoint of Danofloxacin for Glaesserella parasuis in Plasma and in PELF

open access: yesAntibiotics, 2021
Background: In order to establish the clinical breakpoint (CBP) of danofloxacin against G. parasuis, three cutoff values, including epidemiological cutoff value (ECV), pharmacokinetic-pharmacodynamic (PK-PD) cutoff value (COPD) and clinical cutoff value (
Zihui Xu   +11 more
doaj   +1 more source

Chemical characteristics and anti-Escherichia coli mechanism of water-soluble extracts from yeast cell walls

open access: yesBeni-Suef University Journal of Basic and Applied Sciences, 2023
Background Antimicrobial resistance is a threat to global public health and requires the development of new antibiotic alternatives to treat bacterial infection. Infection with Escherichia coli (E.
Yana Liu   +12 more
doaj   +1 more source

A Sensitive and Specific Monoclonal Antibody Based Enzyme-Linked Immunosorbent Assay for the Rapid Detection of Pretilachlor in Grains and the Environment

open access: yesFoods, 2023
Pretilachlor is a chloroacetamide herbicide mainly used for weed and broadleaf weed control in rice, that is widely utilized in China. In order to detect the residue of pretilachlor in the environment and food, a highly sensitive and specific monoclonal ...
Linwei Zhang   +7 more
doaj   +1 more source

Application of a Physiologically Based Pharmacokinetic Model to Develop a Veterinary Amorphous Enrofloxacin Solid Dispersion

open access: yesPharmaceutics, 2021
Zoonotic intestinal pathogens threaten human health and cause huge economic losses in farming. Enrofloxacin (ENR) shows high antibacterial activity against common intestinal bacteria.
Kaixiang Zhou   +7 more
doaj   +1 more source

Rational Use of Danofloxacin for Treatment of Mycoplasma gallisepticum in Chickens Based on the Clinical Breakpoint and Lung Microbiota Shift

open access: yesAntibiotics, 2022
The study was to explore the rational use of danofloxacin against Mycoplasma gallisepticum (MG) based on its clinical breakpoint (CBP) and the effect on lung microbiota.
Shuge Wang   +10 more
doaj   +1 more source

Model Systems of Human Intestinal Flora, to Set Acceptable Daily Intakes of Antimicrobial Residues [PDF]

open access: yes, 2000
The veterinary use of antimicrobial drugs in food producing animals may result in residues in food, that might modify the consumer gut flora. This review compares three model systems that maintain a complex flora of human origin: (i) human flora ...
Corpet, Denis E.
core   +1 more source

The nature and epidemiology of OqxAB, a multidrug efflux pump

open access: yesAntimicrobial Resistance and Infection Control, 2019
Background OqxAB efflux pump has been found to mediate multidrug resistance (MDR) in various bacteria over the past decades. The updates on the nature and epidemiology of OqxAB efflux pump need to be fully reviewed to broaden our understanding of this ...
Jun Li   +6 more
doaj   +1 more source

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