Results 11 to 20 of about 629,459 (301)

PK-PD Modeling and Optimal Dosing Regimen of Acetylkitasamycin against Streptococcus suis in Piglets

Antibiotics, 2022
Streptococcus suis (S. suis) causes severe respiratory diseases in pigs and is also an important pathogen causing hidden dangers to public health and safety.
Anxiong Huang, Feng Mao, Lingli Huang, Shuyu Xie, Yuanhu Pan, Wei Qu, Guyue Cheng, Zhenli Liu, Zonghui Yuan, Dapeng Peng, Haihong Hao   +10 more
doaj   +1 more source

Metabolic Disposition and Elimination of Tritum-Labeled Sulfamethoxazole in Pigs, Chickens and Rats

Metabolites, 2022
Sulfamethoxazole (SMZ), as a sulfa antibiotic, is often used in the treatment of various infectious diseases in animal husbandry. At present, SMZ still has many unresolved problems in the material balance, metabolic pathways, and residual target tissues ...
Jingchao Guo, Yaqi Sun, Yongxia Zhao, Lingli Huang, Dapeng Peng, Haihong Hao, Yanfei Tao, Dongmei Chen, Guyue Cheng, Xu Wang, Yuanhu Pan   +10 more
doaj   +1 more source

The dose regimen formulation of doxycycline hydrochloride and florfenicol injection based on ex vivo pharmacokinetic-pharmacodynamic modeling against the Actinobacillus pleuropneumoniae in pigs

Animal Diseases, 2023
Doxycycline hydrochloride and florfenicol combination (DoxHcl&FF) is an effective treatment for respiratory diseases. In the study, our objective was to evaluate the activity of DoxHcl&FF against Actinobacillus pleuropneumoniae (APP) in porcine pulmonary
Yuanyuan Yuan, Boyu An, Shuyu Xie, Wei Qu, Haihong Hao, Lingli Huang, Wanhe Luo, Jixiang Liang, Dapeng Peng   +8 more
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Exploration of Clinical Breakpoint of Danofloxacin for Glaesserella parasuis in Plasma and in PELF

Antibiotics, 2021
Background: In order to establish the clinical breakpoint (CBP) of danofloxacin against G. parasuis, three cutoff values, including epidemiological cutoff value (ECV), pharmacokinetic-pharmacodynamic (PK-PD) cutoff value (COPD) and clinical cutoff value (
Zihui Xu, Anxiong Huang, Xun Luo, Peng Zhang, Lingli Huang, Xu Wang, Kun Mi, Shiwei Fang, Xiao Huang, Jun Li, Zonghui Yuan, Haihong Hao   +11 more
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Chemical characteristics and anti-Escherichia coli mechanism of water-soluble extracts from yeast cell walls

Beni-Suef University Journal of Basic and Applied Sciences, 2023
Background Antimicrobial resistance is a threat to global public health and requires the development of new antibiotic alternatives to treat bacterial infection. Infection with Escherichia coli (E.
Yana Liu, Baojing Dou, Fayuan Gong, Junpeng Hu, Meifang Zhou, Yuanhu Pan, Xiangyun Wu, Xin Huang, Zhiwen Xie, Haihong Hao, Guyue Cheng, Zhenli Liu, Yulian Wang   +12 more
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A Sensitive and Specific Monoclonal Antibody Based Enzyme-Linked Immunosorbent Assay for the Rapid Detection of Pretilachlor in Grains and the Environment

Foods, 2023
Pretilachlor is a chloroacetamide herbicide mainly used for weed and broadleaf weed control in rice, that is widely utilized in China. In order to detect the residue of pretilachlor in the environment and food, a highly sensitive and specific monoclonal ...
Linwei Zhang, Xiaoyang Yin, Hongfei Yang, Hao Wen, Shiyun Han, Xiaoming Pan, Huaming Li, Dapeng Peng   +7 more
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Application of a Physiologically Based Pharmacokinetic Model to Develop a Veterinary Amorphous Enrofloxacin Solid Dispersion

Pharmaceutics, 2021
Zoonotic intestinal pathogens threaten human health and cause huge economic losses in farming. Enrofloxacin (ENR) shows high antibacterial activity against common intestinal bacteria.
Kaixiang Zhou, Meixia Huo, Wenjin Ma, Kun Mi, Xiangyue Xu, Samah Attia Algharib, Shuyu Xie, Lingli Huang   +7 more
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Rational Use of Danofloxacin for Treatment of Mycoplasma gallisepticum in Chickens Based on the Clinical Breakpoint and Lung Microbiota Shift

Antibiotics, 2022
The study was to explore the rational use of danofloxacin against Mycoplasma gallisepticum (MG) based on its clinical breakpoint (CBP) and the effect on lung microbiota.
Shuge Wang, Anxiong Huang, Yufeng Gu, Jun Li, Lingli Huang, Xu Wang, Yanfei Tao, Zhenli Liu, Congming Wu, Zonghui Yuan, Haihong Hao   +10 more
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Relocation of active site carboxylates in major facilitator superfamily multidrug transporter LmrP reveals plasticity in proton interactions [PDF]

, 2016
The expression of polyspecific membrane transporters is one important mechanism by which cells can obtain resistance to structurally different antibiotics and cytotoxic agents.

core   +2 more sources

Evidence for Establishing the Clinical Breakpoint of Cefquinome against Haemophilus Parasuis in China

Pathogens, 2021
Haemophilus parasuis can cause high morbidity and mortality in swine. Cefquinome possesses excellent antibacterial activity against pathogens causing diseases of the respiratory tract.
Kun Mi, Da Sun, Mei Li, Haihong Hao, Kaixiang Zhou, Zhenli Liu, Zonghui Yuan, Lingli Huang   +7 more
doaj   +1 more source