Results 61 to 70 of about 377,494 (308)
Animal DiseasesThrough structure-based virtual screening, this study identified the botanical compound fangchinoline (FAN) as an inhibitor of the porcine aminopeptidase N (pAPN) receptor and evaluated its anti-transmissible gastroenteritis virus (TGEV) activity ...
Siyi Hu +9 more
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Veterinary Drug Residues in Meat-Related Edible Tissues [PDF]
, 2017 Veterinary drugs are chemicals used to control diseases in animals. If good veterinary practices are followed, these drugs are very useful and make it possible to obtain excellent and abundant food production.
L. Moreno +3 more
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Metal‒organic frameworks for on-demand drug release and precision drug delivery
One Health AdvancesMetal‒organic frameworks (MOFs) are porous materials that combine high stability, large surface areas, excellent porosity, and low toxicity. The rapid development of these drugs has opened new opportunities to enhance drug efficacy with reduced adverse ...
Danlei Hu +6 more
doaj +1 more source
Pharmaceutics, 2022 Antimicrobial resistance is a major public health issue. The pharmacokinetic/pharmacodynamic (PK/PD) model is an essential tool to optimize dosage regimens and alleviate the emergence of resistance.
Kun Mi +8 more
doaj +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Human health aspects of the use of chemicals in aquaculture, with special emphasis on food safety and regulations [PDF]
, 2000 Safe and wholesome food is essential for good health. Therefore, when one considers health issues related to unsafe foods, recorded morbidity and mortality as well as economic losses in a population must be included. Due to their presence in unsafe food,
Samatiwat, Ornrat +2 more
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An Analytical Platform for Near Real-Time Drug Landscape Monitoring using Paraphernalia Residues [PDF]
, 2022 Deaths attributed to drug overdoses are constantly on the rise, but drug trends are frequently changing and often differ across geographical regions. Current analytical techniques are limited in their abilities to rapidly identify drugs that would inform
Elizabeth L, Robinson +4 more
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Drug Residues and Food Safety [PDF]
, 1991 Publication discusses drug residues in food animal products and food safety concerning drug ...
Bagley, Clell V., DVM
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