Results 71 to 80 of about 2,533,448 (256)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

A Broad-Spectrum Monoclonal Antibody-Based Heterologous ic-ELISA for the Detection of Multiple Pyrethroids in Water, Milk, Celery, and Leek

open access: yesFoods
Pyrethroids are one of the most commonly used insecticides worldwide in agriculture, public health, and household products. To monitor the presence of pyrethroids in the environment and in food, a broad-spectrum monoclonal antibody (mAb), CL/CN-1D2, was ...
Sulin Hou   +4 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Pesticide residues in food : 1992, toxicology evaluations, joint meeting of the FAO Panel of Experts on Pesticide Residues in Food and the Environment and the WHO Expert Group on Pesticide Residues, Rome, 21-30 September 1992. Part 2., Toxicology

open access: yes, 1993
Sponsored jointly by FAO and WHO with the support of the International Programme on Chemical SafetyWHO/PCS/93.34422 p.Presents detailed evaluations of the available toxicological and other safety data for eighteen pesticides that have the potential to ...
World Health Organization   +3 more
core  

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Western Hemisphere Drug Policy Commission [website]

open access: yes, 2021
Website of the Western Hemisphere Drug Policy Commission (WHDPC), charged to "evaluate a range of US counternarcotics programs in the Americas and then make recommendations to improve them" -- including a recording and transcript of the group's hearing ...
United States. Western Hemisphere Drug Policy Commission.
core  

Knowledge among Drug Dispensers and Antimalarial Drug Prescribing Practices in Public Health Facilities in Dar es Salaam. [PDF]

open access: yes, 2013
Irrational prescribing and dispensing of antimalarials has been identified as a contributing factor in the emergence of malaria parasites resistant to existing antimalarial drugs.
Kamuhabwa AA   +3 more
core   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Development and evaluation of a medicine-food homology herbal tea for anti-heat stroke efficacy and antioxidant activity

open access: yesFood, Nutrition and Health
Heat stroke (HS) is a life-threatening condition with limited preventive options. Inspired by the classical Qingshu Yiqi Decoction, this study developed a palatable health tea Xiao Qingshu Yiqi Decoction (XQYD) using exclusively medicine-food homology ...
Hanfei Wang   +8 more
doaj   +1 more source

Engineering of a highly efficient quinone-dependent dehydrogenase for deoxynivalenol detoxification and evaluation of its in vivo protective efficacy

open access: yesEcotoxicology and Environmental Safety
To effectively address contamination caused by deoxynivalenol (DON), a strain with high DON-degrading activity was isolated from the black soldier fly larvae gut (BSFLG) and identified as Klebsiella pneumoniae BSFLG-DON15. Results showed that BSFLG-DON15
Fang Li   +6 more
doaj   +1 more source

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