Results 1 to 10 of about 1,055,355 (348)

The Infectious Disease Ontology in the Age of COVID-19 [PDF]

, 2021
The Infectious Disease Ontology (IDO) is a suite of interoperable ontology modules that aims to provide coverage of all aspects of the infectious disease domain, including biomedical research, clinical care, and public health.
Babcock, Shane, Beverley, John, Cowell, Lindsay G., Smith, Barry   +3 more
core   +1 more source

Resisting Bacterial Drug Resistance [PDF]

Chemistry & Biology, 2003
In this issue of Chemistry & Biology, Wright and colleagues report an elegant method for inhibiting enzymes critical for rendering bacteria drug resistant. By using cationic peptides as inhibitors, the authors have exploited two antibacterial mechanisms, making it doubly difficult for microbial retaliation.
openaire   +3 more sources

Pharmacodynamic modelling of in vitro activity of tetracycline against a representative, naturally occurring population of porcine Escherichia coli [PDF]

, 2015
Background The complex relationship between drug concentrations and bacterial growth rates require not only the minimum inhibitory concentration but also other parameters to capture the dynamic nature of the relationship.
Agersø, Yvonne, Ahmad, Amais, Christiansen, Lasse Engbo, Damborg, Peter, Græsbøll, Kaare, Matthews, Louise, Nielsen, Søren Saxmose, Olsen, John Elmerdahl, Toft, Nils, Zachariasen, Camilla   +9 more
core   +4 more sources

Veterinary Medicine Needs New Green Antimicrobial Drugs [PDF]

, 2016
Given that: (1) the worldwide consumption of antimicrobial drugs (AMDs) used in food-producing animals will increase over the coming decades; (2) the prudent use of AMDs will not suffice to stem the rise in human antimicrobial resistance (AMR) of animal ...
Adams, Aidara-Kane, Alvarez, Amidon, Andersson, Andremont, Andremont, Angulo, Ashbolt, Baquero, Bednorz, Bibbal, Bonomo, Brunton, Call, Centers for Disease Control and Prevention, Chantziaras, Chen, Cheng, Cheng, Collignon, DANMAP, de Jong, Dewulf, Duse, Dutil, Edlung, European Food Safety Authority, European Food Safety Authority, European Food Safety Authority, European Medicine Agency, European Medicines Agency, European Medicines Agency, Fairbrother, Food and Drug Administration, Foster, Hansen, Herrick, Heuer, Hofmann, Hojberg, Holman, Horowitz, Huang, Ito, Jacobsen, Kusama, Langlois, Lindecrona, Lipinski, Lipinski, Luo, Marshall, Metz, Midtlyng, Montanari, Naess, Nielsen, Nord, O’Brien, O’Connor, Panagiotidis, Phillips, Pijpers, Pollet, Rashid, Rashid, Ratz, Rioux, Roof, Rose, Sakaeda, Sarmah, Singer, Smith, Sparo, Stamey, Subbiah, Takenouchi, Taverne, Thiele-Bruhn, Tolls, Toutain, Toutain, Toutain, Toutain, Toutain, Trobos, Van Boeckel, van den Bogaard, van der Waaij, Wellington, Whitman, World Health Organisation, World Health Organisation, Yazdankhah, Yusof, Zhang   +97 more
core   +6 more sources

Multistrain models predict sequential multidrug treatment strategies to result in less antimicrobial resistance than combination treatment [PDF]

, 2016
Background Combination treatment is increasingly used to fight infections caused by bacteria resistant to two or more antimicrobials. While multiple studies have evaluated treatment strategies to minimize the emergence of resistant strains for single ...
Ahmad, Amais, Christiansen, Lasse Engbo, Græsbøll, Kaare, Matthews, Louise, Nielsen, Søren Saxmose, Olsen, John Elmerdahl, Toft, Nils, Zachariasen, Camilla   +7 more
core   +4 more sources

Oxygen Limitation Enhances the Antimicrobial Activity of Fosfomycin in Pseudomonas aeruginosa Following Overexpression of glpT Which Encodes Glycerol-3-Phosphate/Fosfomycin Symporter

Frontiers in Microbiology, 2018
Fosfomycin is resurfacing as a “last resort drug” to treat infections caused by multidrug resistant pathogens. This drug has a remarkable benefit in that its activity increases under oxygen-limited conditions unlike other commonly used antimicrobials ...
Hidetada Hirakawa, Kumiko Kurabayashi, Koichi Tanimoto, Haruyoshi Tomita, Haruyoshi Tomita   +4 more
doaj   +1 more source

Pathogens and drug resistance in bacterial diarrhea in Lishui City from 2015 to 2019

Shanghai yufang yixue, 2022
ObjectiveTo determine the pathogens and drug resistance in patients with bacterial diarrhea in Lishui City of Zhejiang Province from 2015 to 2019， and provide scientific evidence for prevention and treatment of bacterial diarrhea.MethodFecal specimens ...
ZHANG Qiang, LIN Feifei, LUO Shunbin, ZHENG Shu, LIN Yuyu   +4 more
doaj   +1 more source

Classification of Clinical Isolates of Klebsiella pneumoniae Based on Their in vitro Biofilm Forming Capabilities and Elucidation of the Biofilm Matrix Chemistry With Special Reference to the Protein Content

Frontiers in Microbiology, 2019
Klebsiella pneumoniae is a human pathogen, capable of forming biofilms on abiotic and biotic surfaces. The limitations of the therapeutic options against Klebsiella pneumoniae is actually due to its innate capabilities to form biofilm and harboring ...
Ashish Kumar Singh, Ashish Kumar Singh, Shivangi Yadav, Brijesh Singh Chauhan, Nabarun Nandy, Rajan Singh, Kaushik Neogi, Jagat Kumar Roy, Saripella Srikrishna, Rakesh Kumar Singh, Pradyot Prakash   +10 more
doaj   +1 more source

Potency of marbofloxacin for pig pneumonia pathogens Actinobacillus pleuropneumoniae and Pasteurella multocida: Comparison of growth media [PDF]

, 2017
Pharmacodynamic properties of marbofloxacin were established for six isolates each of the pig respiratory tract pathogens, Actinobacillus pleuropneumoniae and Pasteurella multocida.
Dorey, L, Hobson, S, Lees, P
core   +1 more source

Isolation and characterization of multiple drug resistance bacterial pathogens from waste water in hospital and non-hospital environments, Northwest Ethiopia

BMC Research Notes, 2014
The importance of bacterial isolates from waste water environment as a reservoir of antibiotic resistance and a potential source of novel resistance genes to clinical pathogens is underestimated.
F. Moges, Mengistu Endris, Yeshambel Belyhun, Walelegn Worku   +3 more
semanticscholar   +1 more source