Results 31 to 40 of about 4,798,630 (303)

Molecular mechanisms of drug resistance in natural Leishmania populations vary with genetic background [PDF]

, 2012
The evolution of drug-resistance in pathogens is a major global health threat. Elucidating the molecular basis of pathogen drug-resistance has been the focus of many studies but rarely is it known whether a drug-resistance mechanism identified is ...
Sylke Müller, Hideo Imamura (62469), Dujardin, J., Khanal, Basudha, Brunker, K., Brunker, Kirstyn, Kirstyn Brunker (181178), Graham H. Coombs (164011), Suman Rijal (181185), Imamura, Hideo, Jean-Claude Dujardin, M\ufcller, Sylke, Dujardin, Jean-Claude, Dujardin, J. C., Coombs, G. H., Muller, S., Jean-Claude Dujardin (56958), Decuypere, S., Coombs, G.H., Vanaerschot, M., Decuypere, Saskia, Coombs, Graham H, Rijal, S., Manu Vanaerschot, Sylke Müller (37476), Basudha Khanal, Khanal, B., Hideo Imamura, Kirstyn Brunker, Müller, Sylke, Coombs, Graham H., Vanaerschot, Manu, Imamura, H., Rijal, Suman, Saskia Decuypere, Basudha Khanal (181181), Saskia Decuypere (181176), Manu Vanaerschot (109210), Suman Rijal, Graham H Coombs   +39 more
core   +5 more sources

DRUG-RESISTANCE OF BACTERIS

The KITAKANTO Medical Journal, 1963
In the field study many types of drug-resistant E. coli, Shigella and Citrobacter were isolated by this laboratory. And seven types of transmissible drug-resistance factor were obtained; R(TC) R(SM), R(CM. TC), R(SM. SA), R(CM. SM SA), R(TC. SM. SA) and R(CM. TC.SM. SA). The R(CM) factor was segregated from (CM.
openaire   +4 more sources

Novel Multidrug-Resistant Enterococcal Mobile Linear Plasmid pELF1 Encoding vanA and vanM Gene Clusters From a Japanese Vancomycin-Resistant Enterococci Isolate

Frontiers in Microbiology, 2019
Vancomycin-resistant enterococci are troublesome pathogens in clinical settings because of few treatment options. A VanA/VanM-type vancomycin-resistant Enterococcus faecium clinical isolate was identified in Japan. This strain, named AA708, harbored five
Yusuke Hashimoto, Makoto Taniguchi, Kazuma Uesaka, Takahiro Nomura, Hidetada Hirakawa, Koichi Tanimoto, Kiyoko Tamai, Genjie Ruan, Bo Zheng, Haruyoshi Tomita, Haruyoshi Tomita   +10 more
doaj   +1 more source

Transferable drug resistance plasmids in fish-pathogenic bacteria [PDF]

, 2000
Chemotherapeutic agents have been developed for treating bacterial infections and have been widely used for cultured fish for the last 30 years in Japan.
Aoki, Takashi
core   +1 more source

Can We Prevent Antimicrobial Resistance by Using Antimicrobials Better? [PDF]

, 2013
Since their development over 60 years ago, antimicrobials have become an integral part of healthcare practice worldwide. Recently, this has been put in jeopardy by the emergence of widespread antimicrobial resistance, which is one of the major problems ...
Germander Soothill, Hu, Y, Yanmin Hu, Soothill, G, Anthony Coates, Coates, A   +5 more
core   +1 more source

Structural and functional studies of bacterial outer membrane proteins [PDF]

, 2010
This thesis studies two particular bacterial outer membrane proteins called OmpC and Wzi, focusing on their expression, purification, crystallization and X-ray structure determination.
Lou, Hubing
core   +2 more sources

Expression of DNA Gyrase at mRNA Levels and Antibacterial Effect of FluoroquinoloneDerived Compounds on Two Antibiotic Resistant Bacteria; Staphylococcus aureus and Enterococcus faecalis [PDF]

Journal of Clinical and Diagnostic Research, 2019
Introduction: Fluoroquinolones are a form of antibiotics capable of influencing DNA Gyrase of bacteria. Any alteration in the structure of current fluoroquinolone antibacterials may provide a better effect on the growth inhibition of bacteria.
Shokrollah Assar, Ali Darehkordi, Mohammad Moradi, Mahmood Sheikh Fathollahi, Soudeh Khanamani Falahati Pour, Gholamhossein Hassanshahi   +5 more
doaj   +1 more source

The Tol-Pal System of Uropathogenic Escherichia coli Is Responsible for Optimal Internalization Into and Aggregation Within Bladder Epithelial Cells, Colonization of the Urinary Tract of Mice, and Bacterial Motility

Frontiers in Microbiology, 2019
Urinary tracts infection (UTI) caused by uropathogenic Escherichia coli (UPEC) is a common infectious disease. With the shortage of new antimicrobial agents, the increase in UPEC resistance to commonly used drugs, such as fluoroquinolones and β-lactams ...
Hidetada Hirakawa, Kazutomo Suzue, Kumiko Kurabayashi, Haruyoshi Tomita, Haruyoshi Tomita   +4 more
doaj   +1 more source

KvarQ: targeted and direct variant calling from fastq reads of bacterial genomes [PDF]

, 2014
High-throughput DNA sequencing produces vast amounts of data, with millions of short reads that usually have to be mapped to a reference genome or newly assembled.
Steiner, Andreas, Sebastien Gagneux, David Stucki, Andreas Steiner, Borrell, Sonia, Stucki, David, Sonia Borrell, Gagneux, Sebastien, Mireia Coscolla, Coscolla, Mireia   +9 more
core   +1 more source

Genomic dissection of nosocomial multiclonal-outbreak by carbapenem-resistant Pseudomonas aeruginosa strains in a tertiary children’s hospital in Japan

Journal of Global Antimicrobial Resistance
Objective: Carbapenem-resistant Pseudomonas aeruginosa (CRPA) is an important antimicrobial-resistant bacterial pathogen. We observed an increase in the detection rate of CRPA isolates at a tertiary children’s hospital in Japan.
Akihiko Shimizu, Jun Kurushima, Koichi Tanimoto, Naoko Tomie, Yusuke Hashimoto, Takahiro Nomura, Natsuko Ota, Hidetada Hirakawa, Haruyoshi Tomita   +8 more
doaj   +1 more source