Results 21 to 30 of about 1,013,456 (328)

Overcoming the challenges of cancer drug resistance through bacterial-mediated therapy. [PDF]

, 2019
Despite tremendous efforts to fight cancer, it remains a major public health problem and a leading cause of death worldwide. With increased knowledge of cancer pathways and improved technological platforms, precision therapeutics that specifically target
Bivona, Trever G, Chang, Samantha, Hernández, Amanda C, Keasling, Jay D, Kothari, Ankita, Mao, Jian-Hua, Snijders, Antoine M, Wang, Jessica, Zargar, Amin   +8 more
core   +1 more source

Oxygen Limitation Enhances the Antimicrobial Activity of Fosfomycin in Pseudomonas aeruginosa Following Overexpression of glpT Which Encodes Glycerol-3-Phosphate/Fosfomycin Symporter

Frontiers in Microbiology, 2018
Fosfomycin is resurfacing as a “last resort drug” to treat infections caused by multidrug resistant pathogens. This drug has a remarkable benefit in that its activity increases under oxygen-limited conditions unlike other commonly used antimicrobials ...
Hidetada Hirakawa, Kumiko Kurabayashi, Koichi Tanimoto, Haruyoshi Tomita, Haruyoshi Tomita   +4 more
doaj   +1 more source

Pathogens and drug resistance in bacterial diarrhea in Lishui City from 2015 to 2019

Shanghai yufang yixue, 2022
ObjectiveTo determine the pathogens and drug resistance in patients with bacterial diarrhea in Lishui City of Zhejiang Province from 2015 to 2019， and provide scientific evidence for prevention and treatment of bacterial diarrhea.MethodFecal specimens ...
ZHANG Qiang, LIN Feifei, LUO Shunbin, ZHENG Shu, LIN Yuyu   +4 more
doaj   +1 more source

Classification of Clinical Isolates of Klebsiella pneumoniae Based on Their in vitro Biofilm Forming Capabilities and Elucidation of the Biofilm Matrix Chemistry With Special Reference to the Protein Content

Frontiers in Microbiology, 2019
Klebsiella pneumoniae is a human pathogen, capable of forming biofilms on abiotic and biotic surfaces. The limitations of the therapeutic options against Klebsiella pneumoniae is actually due to its innate capabilities to form biofilm and harboring ...
Ashish Kumar Singh, Ashish Kumar Singh, Shivangi Yadav, Brijesh Singh Chauhan, Nabarun Nandy, Rajan Singh, Kaushik Neogi, Jagat Kumar Roy, Saripella Srikrishna, Rakesh Kumar Singh, Pradyot Prakash   +10 more
doaj   +1 more source

Emergence of Antimicrobial Resistance, Causes, Molecular Mechanisms, and Prevention Strategies: A Bovine Perspective [PDF]

, 2019
Emergence of the resistance in microbial population is a major threat to both animal and human health. In bovine, the development of microbial resistance is a persistent threat for health especially in the form of zoonotic pandemics due to viral and ...
-Mustafa, Behar-E, -Rehman, Shahid-Ur, Ashraf, Muhammad, Ashraf, Muhammad Adnan, Bashir, Muhammad Khalid   +4 more
core   +1 more source

Isolation and characterization of multiple drug resistance bacterial pathogens from waste water in hospital and non-hospital environments, Northwest Ethiopia

BMC Research Notes, 2014
The importance of bacterial isolates from waste water environment as a reservoir of antibiotic resistance and a potential source of novel resistance genes to clinical pathogens is underestimated.
F. Moges, Mengistu Endris, Yeshambel Belyhun, Walelegn Worku   +3 more
semanticscholar   +1 more source

Survey of drug resistance associated gene mutations in Mycobacterium tuberculosis, ESKAPE and other bacterial species

Scientific Reports, 2020
Tuberculosis treatment includes broad-spectrum antibiotics such as rifampicin, streptomycin and fluoroquinolones, which are also used against other pathogenic bacteria.
A. Ghosh, Saran N., S. Saha
semanticscholar   +1 more source

Pneumonia Caused by Klebsiella spp. in 46 Horses. [PDF]

, 2015
BackgroundKlebsiella spp. are implicated as a common cause of bacterial pneumonia in horses, but few reports describe clinical presentation and disease progression.Hypothesis/objectivesTo describe the signalment, clinicopathologic data, radiographic and ...
Aleman, M, Byrne, BA, Estell, KE, Kass, PH, Kozikowski, T, Reilly, CM, Swain, EA, Young, A   +7 more
core   +1 more source

Novel Multidrug-Resistant Enterococcal Mobile Linear Plasmid pELF1 Encoding vanA and vanM Gene Clusters From a Japanese Vancomycin-Resistant Enterococci Isolate

Frontiers in Microbiology, 2019
Vancomycin-resistant enterococci are troublesome pathogens in clinical settings because of few treatment options. A VanA/VanM-type vancomycin-resistant Enterococcus faecium clinical isolate was identified in Japan. This strain, named AA708, harbored five
Yusuke Hashimoto, Makoto Taniguchi, Kazuma Uesaka, Takahiro Nomura, Hidetada Hirakawa, Koichi Tanimoto, Kiyoko Tamai, Genjie Ruan, Bo Zheng, Haruyoshi Tomita, Haruyoshi Tomita   +10 more
doaj   +1 more source

Antibiotic resistance in ocular bacterial infections: an integrative review of ophthalmic chloramphenicol

Tropical Medicine and Health, 2023
Introduction Chloramphenicol is a broad-spectrum antibiotic widely used for treating ophthalmic infections, but concerns about rising bacterial resistance to chloramphenicol have been observed due to its frequent use as an over-the-counter medication ...
Babatunde Ismail Bale, Emmanuel Ebuka Elebesunu, Pirakalai Manikavasagar, Favour Obianuju Agwuna, Isaac Olushola Ogunkola, Alhaji Umar Sow, Don Eliseo Lucero-Prisno   +6 more
doaj   +1 more source