Results 41 to 50 of about 780,165 (288)

Expression of DNA Gyrase at mRNA Levels and Antibacterial Effect of FluoroquinoloneDerived Compounds on Two Antibiotic Resistant Bacteria; Staphylococcus aureus and Enterococcus faecalis [PDF]

Journal of Clinical and Diagnostic Research, 2019
Introduction: Fluoroquinolones are a form of antibiotics capable of influencing DNA Gyrase of bacteria. Any alteration in the structure of current fluoroquinolone antibacterials may provide a better effect on the growth inhibition of bacteria.
Shokrollah Assar, Ali Darehkordi, Mohammad Moradi, Mahmood Sheikh Fathollahi, Soudeh Khanamani Falahati Pour, Gholamhossein Hassanshahi   +5 more
doaj   +1 more source

Biofilm-Associated Multi-Drug Resistance in Hospital-Acquired Infections: A Review

Infection and Drug Resistance, 2022
Biofilm-related multi-drug resistance (MDR) is a major problem in hospital-acquired infections (HAIs) that increase patient morbidity and mortality rates and economic burdens such as high healthcare costs and prolonged hospital stay.
M. Assefa, Azanaw Amare
semanticscholar   +1 more source

Defence against bacterial drug resistance. [PDF]

BMJ, 1976
Everyone knows that acquired microbic resistance is the Achilles heel of chemotherapy. All living things can acquire some resistance to noxious agents-man to morphine, for instance. Bacteria are no exception: they can become more resistant in some degree even to ordinary germicides.
openaire   +3 more sources

Drug resistance, bacterial; bacterial infections; anti-bacterial agents; Streptococcus pyogenes; surgery, oral; mouth.

Journal of Oral Research, 2020
Orofacial infections are considered as one of most common infections and need rapid and adequate treatment as they affect a very delicate region and are associated with serious life-threatening complications.
Noor Abdullah Sulaiman, Sabah Abdulaziz Issa, Najwa Abdul Razzak   +2 more
doaj   +1 more source

Antibiotics and Bacterial Resistance—A Short Story of an Endless Arms Race

International Journal of Molecular Sciences, 2023
Despite the undisputed development of medicine, antibiotics still serve as first-choice drugs for patients with infectious disorders. The widespread use of antibiotics results from a wide spectrum of their actions encompassing mechanisms responsible for:
A. Baran, A. Kwiatkowska, L. Potocki
semanticscholar   +1 more source

Interactions of Antibiotics and Methanolic Crude Extracts of Afzelia Africana (Smith.) Against Drug Resistance Bacterial Isolates

International Journal of Molecular Sciences, 2011
Infection due to multidrug resistance pathogens is difficult to manage due to bacterial virulence factors and because of a relatively limited choice of antimicrobial agents.
O. Aiyegoro, A. Adewusi, S. Oyedemi, D. Akinpelu, A. Okoh   +4 more
semanticscholar   +1 more source

The Tol-Pal System of Uropathogenic Escherichia coli Is Responsible for Optimal Internalization Into and Aggregation Within Bladder Epithelial Cells, Colonization of the Urinary Tract of Mice, and Bacterial Motility

Frontiers in Microbiology, 2019
Urinary tracts infection (UTI) caused by uropathogenic Escherichia coli (UPEC) is a common infectious disease. With the shortage of new antimicrobial agents, the increase in UPEC resistance to commonly used drugs, such as fluoroquinolones and β-lactams ...
Hidetada Hirakawa, Kazutomo Suzue, Kumiko Kurabayashi, Haruyoshi Tomita, Haruyoshi Tomita   +4 more
doaj   +1 more source

In Silico Screen Identifies a New Family of Agonists for the Bacterial Mechanosensitive Channel MscL

Antibiotics, 2022
MscL is a highly conserved mechanosensitive channel found in the majority of bacterial species, including pathogens. It functions as a biological emergency release valve, jettisoning solutes from the cytoplasm upon acute hypoosmotic stress.
Robin Wray, Paul Blount, Junmei Wang, Irene Iscla   +3 more
doaj   +1 more source

Multi Drug Resistance Bacterial Isolates of Surgical Site Infection

, 2014
Multi drug resistance microorganism is considered to be one of the major health problems. The aim of this study was to determine antibiotic susceptibility pattern of bacterial pathogens of surgical site infection.
C. P. Bhatt, R. Baidya, P. Karki, R. Shah, Rashiak Miya, Pratima Mahashate, K. Mishra   +6 more
semanticscholar   +1 more source

Common themes in antimicrobial and anticancer drug resistance

Frontiers in Microbiology, 2022
Antimicrobial and anticancer drug resistance represent two of the main global challenges for the public health, requiring immediate practical solutions.
M. Chifiriuc, Roxana Filip, M. Constantin, G. Pîrcălăbioru, C. Bleotu, L. Burlibașa, E. Ionica, N. Corcionivoschi, G. Mihăescu   +8 more
semanticscholar   +1 more source