Results 71 to 80 of about 780,066 (189)

Adenosine Monophosphate as a Metabolic Adjuvant Enhances Antibiotic Efficacy against Drug-Resistant Bacterial Pathogens

Pharmaceuticals
Global bacterial infections are on the rise, and drug resistance to bacteria is gradually rendering existing antibiotics ineffective. Therefore, the discovery of new strategies is urgently needed.
Wenxuan Zhang, Zhenyi Wu, Zulifukeer Maituersong, Ting Wang, Yubin Su   +4 more
doaj   +1 more source

Iranians’ Self-Report Knowledge and Practice about Arbitrary Use of Antibiotics [PDF]

Journal of Clinical and Diagnostic Research, 2017
Introduction: Scientific studies revealed a high prevalence rate of self-medication among Iranians, nevertheless there are few studies exploring the factors affecting on.
Kazem Hosseinzadeh, Jalil Azimian
doaj   +1 more source

Whole-genome sequencing targets drug-resistant bacterial infections [PDF]

Human Genomics, 2015
During the past two decades, the technological progress of whole-genome sequencing (WGS) had changed the fields of Environmental Microbiology and Biotechnology, and, currently, is changing the underlying principles, approaches, and fundamentals of Public Health, Epidemiology, Health Economics, and national productivity.
N. V. Punina, N. M. Makridakis, M. A. Remnev, A. F. Topunov   +3 more
openaire   +3 more sources

Antimicrobial drug resistance among clinically relevant bacterial isolates in sub-Saharan Africa: a systematic review.

Journal of Antimicrobial Chemotherapy, 2014
BACKGROUND Little is known about the prevalence of antimicrobial resistance (AMR) amongst bacterial pathogens in sub-Saharan Africa (sSA), despite calls for continent-wide surveillance to inform empirical treatment guidelines.
S. Leopold, F. van Leth, H. Tarekegn, C. Schultsz   +3 more
semanticscholar   +1 more source

Interventions on Metabolism: Making Antibiotic-Susceptible Bacteria

mBio, 2017
Antibiotics act on bacterial metabolism, and antibiotic resistance involves changes in this metabolism. Interventions on metabolism with drugs might therefore modify drug susceptibility and drug resistance.
Fernando Baquero, José-Luis Martínez
doaj   +1 more source

The Association between Mycobacterium Tuberculosis Genotype and Drug Resistance in Peru.

PLoS ONE, 2015
BackgroundThe comparison of Mycobacterium tuberculosis bacterial genotypes with phenotypic, demographic, geospatial and clinical data improves our understanding of how strain lineage influences the development of drug-resistance and the spread of ...
Louis Grandjean, Tomotada Iwamoto, Anna Lithgow, Robert H Gilman, Kentaro Arikawa, Noriko Nakanishi, Laura Martin, Edith Castillo, Valentina Alarcon, Jorge Coronel, Walter Solano, Minoo Aminian, Claudia Guezala, Nalin Rastogi, David Couvin, Patricia Sheen, Mirko Zimic, David A J Moore   +17 more
doaj   +1 more source

Investigating colistin drug resistance: The role of high-throughput sequencing and bioinformatics [version 2; peer review: 2 approved]

F1000Research, 2019
Bacterial infections involving antibiotic-resistant gram-negative bacteria continue to increase and represent a major global public health concern.
Dickson Aruhomukama, Ivan Sserwadda, Gerald Mboowa   +2 more
doaj   +1 more source

Antiepileptic drug carbamazepine promotes horizontal transfer of plasmid-borne multi-antibiotic resistance genes within and across bacterial genera

The ISME Journal, 2018
Antibiotic resistance is a severe global threat for public health, causing around 700,000 deaths per year. Horizontal gene transfer (HGT) is one of the most significant pathways to disseminate antibiotic resistance.
Yue Wang, Ji Lu, Likai Mao, Jie Li, Zhiguo Yuan, P. Bond, Jianhua Guo   +6 more
semanticscholar   +1 more source

Editorial: Antibiotic potentiators against drug-resistant pathogens: Discovery, development and clinical applications

Frontiers in Microbiology, 2023
Bhabatosh Das, Dinesh Mahajan, Jasna Rakonjac   +2 more
doaj   +1 more source

Inhibiting Bacterial Drug Efflux Pumps via Phyto-Therapeutics to Combat Threatening Antimicrobial Resistance

Frontiers in Microbiology, 2018
Antibiotics, once considered the lifeline for treating bacterial infections, are under threat due to the emergence of threatening antimicrobial resistance (AMR). These drug-resistant microbes (or superbugs) are non-responsive to most of the commonly used
V. Shriram, T. Khare, R. Bhagwat, R. Shukla, Vinay Kumar   +4 more
semanticscholar   +1 more source