Results 81 to 90 of about 1,013,456 (328)

The Mechanism of Bacterial Resistance and Potential Bacteriostatic Strategies

Antibiotics, 2022
Bacterial drug resistance is rapidly developing as one of the greatest threats to human health. Bacteria will adopt corresponding strategies to crack the inhibitory effect of antibiotics according to the antibacterial mechanism of antibiotics, involving ...
Fusheng Zhang, Wei Cheng
semanticscholar   +1 more source

DRUG-RESISTANCE OF BACTERIS

The KITAKANTO Medical Journal, 1963
In the field study many types of drug-resistant E. coli, Shigella and Citrobacter were isolated by this laboratory. And seven types of transmissible drug-resistance factor were obtained; R(TC) R(SM), R(CM. TC), R(SM. SA), R(CM. SM SA), R(TC. SM. SA) and R(CM. TC.SM. SA). The R(CM) factor was segregated from (CM.
openaire   +5 more sources

Multidrug resistance: Versatile drug sensors of bacterial cells [PDF]

Current Biology, 1999
One way that bacteria resist antimicrobial agents involves 'drug sensors', proteins that bind a range of structurally unrelated antimicrobial drugs and induce expression of multidrug resistance pumps. The basis for drug recognition is now becoming clear from the recently determined crystal structure of a drug sensor.
openaire   +3 more sources

Antimicrobial peptides for combating drug-resistant bacterial infections

Drug Resistance Updates, 2023
The problem of drug resistance due to long-term use of antibiotics has been a concern for years. As this problem grows worse, infections caused by multiple bacteria are expanding rapidly and are extremely detrimental to human health. Antimicrobial peptides (AMPs) are a good alternative to current antimicrobials with potent antimicrobial activity and ...
Jiaqi Xuan, Weiguo Feng, Jiaye Wang, Ruichen Wang, Bowen Zhang, Letao Bo, Zhe-Sheng Chen, Hui Yang, Leming Sun   +8 more
openaire   +2 more sources

Crosstalk between gut microbiota and tumor: tumors could cause gut dysbiosis and metabolic imbalance

Molecular Oncology, EarlyView.
In this research, we analyzed the relationship between gut microbiota and tumor. We discovered that both subcutaneous and metastatic tumors would alter the composition and metabolic function of gut microbiota. Meanwhile, fecal microbiota transplantation also indicated the anti‐tumor role of the gut microbiota, revealing the crosstalk between tumor and ...
Siyuan Zhang, Haimei Wen, Ying Chen, Jingya Ning, Di Hu, Yujiao Dong, Chenyu Yao, Bo Yuan, Shuanying Yang   +8 more
wiley   +1 more source

Could Public Restrooms Be an Environment for Bacterial Resistomes? [PDF]

, 2013
PMCID: PMC3547874This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
A Bizzini, A Fajardo, A Gardner, A Rahman, AA Vickers, BM Marshall, C Benagli, Charlotte A. Russell, CP Gerba, D Nathwani, E Carbonnelle, E Scott, EGA Fredheim, F Koksal, GD Wright, GD Wright, GE Flores, H Goto, Hermine V. Mkrtchyan, J Barker, J Karakulska, JY Park, K Fox, K Kummerer, L Nelson, M Cizman, M Kliem, M Nakib Al, MF Mendes, MN Alekshun, Nan Wang, Patrick M. Schlievert, PJ Turnbaugh, Ronald R. Cutler, S Bocher, S Miyakis, SB Levy, TL Overman, Y Katayama, Y Kondo, YW Miller   +40 more
core   +5 more sources

Evolved bacterial resistance against fluoropyrimidines can lower chemotherapy impact in the Caenorhabditis elegans host

eLife, 2020
Metabolism of host-targeted drugs by the microbiome can substantially impact host treatment success. However, since many host-targeted drugs inadvertently hamper microbiome growth, repeated drug administration can lead to microbiome evolutionary ...
Brittany Rosener, Serkan Sayin, Peter O Oluoch, Aurian P García González, Hirotada Mori, Albertha JM Walhout, Amir Mitchell   +6 more
doaj   +1 more source

Bacterial Antibiotic Resistance: The Most Critical Pathogens

Pathogens, 2021
Antibiotics have made it possible to treat bacterial infections such as meningitis and bacteraemia that, prior to their introduction, were untreatable and consequently fatal.
G. Mancuso, A. Midiri, E. Gerace, C. Biondo   +3 more
semanticscholar   +1 more source

Inhibition of acyl‐CoA synthetase long‐chain isozymes decreases multiple myeloma cell proliferation and causes mitochondrial dysfunction

Molecular Oncology, EarlyView.
Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy, Heather Fairfield, Victoria E. DeMambro, Samaa Fadel, Carlos A. Gartner, Michelle Karam, Christian Potts, Princess Rodriguez, Ya‐Wei Qiang, Habib Hamidi, Xiangnan Guan, Calvin P. H. Vary, Michaela R. Reagan   +12 more
wiley   +1 more source

Limited effect of patient and disease characteristics on compliance with hospital antimicrobial guidelines [PDF]

, 2005
Objective: Physicians frequently deviate from guidelines that promote prudent use of antimicrobials. We explored to what extent patient and disease characteristics were associated with compliance with guideline recommendations for three common infections.
A Alvarez, DJ McCaig, DT Bearden, EH Ibrahim, EM Brown, European Antimicrobial Resistance Surveillance System, Flora M. Haaijer-Ruskamp, GL Mandell, IC Gyssens, IM Gould, J Avorn, J Cobo, J Gans de, J Hatton, JG Bartlett, John E. Degener, JW Warren, Marian Laseur, ME Kasteren van, ME Kasteren van, Peter G. M. Mol, Petra Denig, PGM Mol, PGM Mol, PGM Mol, PP Cook, Prashant V. NannanPanday, R Grol, Rijk O. B. Gans, RJ Meyer, RP Wenzel, SE Buijk, SJ Atlas, SL Bronzwaer, W Kasje, WA Knaus, WE Stamm   +36 more
core   +3 more sources