Results 151 to 160 of about 4,538,104 (325)
MBX-7591: a promising drug candidate against drug-resistant fungal infections
mBioABSTRACT Invasive fungal infections (IFIs) caused by pathogenic fungi pose a significant public health concern, particularly for immunocompromised individuals. Mortality rates for IFIs remain high, and currently available treatment options are limited.
Nivea Pereira de Sa, Maurizio Del Poeta
openaire +3 more sources
Genetics of fungal resistance to systemic fungicides [PDF]
, 1977 Since the introduction of the systemic fungicides, fungicide resistance has become a serious problem in plant disease control. This study was carried out in order to contribute to the knowledge about the genetics of fungal resistance to fungicides both ...
Tuyl, J.M., van, van Tuyl, J.M.
core
Beyond resistance: antifungal heteroresistance and antifungal tolerance in fungal pathogens
Current Opinion in MicrobiologyFungal infections are increasing globally, causing alarmingly high mortality and economic burden. In addition to antifungal resistance, other more subtle drug responses appear to increase the likelihood of treatment failures.
Feng Yang, J. Berman
semanticscholar +1 more source
Characterisation and modulation of drug resistance in lung cancer cell lines [PDF]
, 2010 Chemotherapy drug resistance is a major obstacle in the treatment of cancer. It can result from an increase in levels of cellular drug efflux pumps such as P-glycoprotein (P-gp).
Dunne, Gráinne
core +2 more sources
Using Synthetic Glycans to Investigate Anti‐Glycan Antibodies and Explore Their Medical Potential
Angewandte Chemie International Edition, EarlyView.Anti‐glycan antibodies are essential in health and disease. Access to novel glycan structures paves the way for progress in antibody profiling for biomarker discovery, antibody development, and vaccine design. We summarize the strategies to synthesize and utilize synthetic glycans for the development and application of anti‐glycan antibodies in basic ...
Fabienne Weber +4 more
wiley +1 more source
Journal of Applied Polymer Science, EarlyView.PLA and PCL ocular implants prepared by tape casting and electrospinning provide sustained dexamethasone release with distinct release profiles governed by polymer type and processing method. The relationship between polymer structure, degradation behavior, and drug release demonstrates the potential of these fabrication techniques for controlled ...
Renata Bochanoski +6 more
wiley +1 more source
Animal Research and One Health, EarlyView.Heat stress disrupts gut microbial balance in poultry, impairing nutrient absorption and immunity. This review outlines the interplay between thermal stress and microbiome dynamics and discusses integrative mitigation strategies, probiotics, phytogenics, cooling systems, and genetic adaptation to enhance poultry resilience.
O. E. Oke +9 more
wiley +1 more source
[Drug resistance in the treatment of invasive fungal infections].
Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 2008 The incidence of invasive fungal infections is increasing in parallel with an increase of patients with immunodeficiencies. Resistance to these drugs is becoming a problem in spite of increased and improved treatment options.Literature retrieved from Medline and personal findings and experience form the basis for this article.Candida albicans is still ...
Ingvild, Nordøy, Peter, Gaustad
openaire +1 more source
Animal Research and One Health, EarlyView.Gastrointestinal nematode infections damage the gastrointestinal epithelial tissues of ruminants, affecting nutrient utilization and overall production performance. This review outlines host‐gastrointestinal nematode interactions and discusses integrated control strategies, including nutritional supplementation, grazing management, vaccines, and ...
Wenxun Chen +5 more
wiley +1 more source