Results 191 to 200 of about 361,408 (311)

Microbes and medicines: interrelationships between pharmaceuticals and the gut microbiome. [PDF]

Gut Microbes
Al-Btoosh S, Donnelly RF, Kelly SA.
europepmc   +1 more source

Precise Construction of an Antimicrobial Peptide Targeting Bacterial Cell Membranes Derived From Natural Peptides

Advanced Science, EarlyView.
An AMP (P 3‐3R‐8I) based on natural peptides, which can target bacterial cell membranes, was precisely constructed via amino acid mutation. P 3‐3R‐8I exhibits antibacterial capability which could be attributed to the ability of P 3‐3R‐8I to quickly penetrate bacterial cell membranes and then to bind to bacterial DNA.
Jiaqi Huang, Bohao Liu, Xingzhuo Zhu, Deqian Qiao, Sizhe Chen, Xiaoyan Zeng, Qingqing Yang, Zihuan Wei, Yinjuan Huang, Jizhao Wang, Guangjian Zhang, Qiuyu Gong   +11 more
wiley   +1 more source

Phage therapy and the microbiome in hematologic malignancies: opportunities, mechanisms, and early evidence. [PDF]

J Cancer Res Clin Oncol
Zhang J, Liu J, Bayani A.
europepmc   +1 more source

Photothermal–Immunomodulatory Hydrogel Reinforced by Ti3C2/ZnAl‐LDH Nanoplatform for Eradicating MRSA and Promoting Diabetic Wound Healing

Advanced Science, EarlyView.
A NETs‐inspired Ti3C2/LDH hydrogel integrates trapping, ROS boosting, and M2‐immunomodulation for MRSA‐infected wound repair. ABSTRACT MRSA infections give rise to chronic cutaneous and advance into profound tissue invasions, including osteomyelitis and sepsis—conditions for which existing clinical interventions offer only limited efficacy. The utility
Qiang Shi, Renliang Zhao, Jia Wang, Zhenchen Xiong, Xiangtian Deng, Cheng Zheng, Wenzhi Zhang   +6 more
wiley   +1 more source

Biofilms: from the cradle of life to life support. [PDF]

NPJ Biofilms Microbiomes
Baxter KJ, Sas E, Clark KB, Walsh M, Pradeep N, Batool A, Naney C, Vargas Cruz MA, Kennerdale N, Das K, Shi Z, Kelam A, Verma V, Simões MF, Neefs D, Ravichandran V, Tirumalai MR, Barcenilla BB, Macori G, Gonzalez E, Sikes B, Karouia F, Brereton NJB.   +22 more
europepmc   +1 more source

Rescuing Mitochondrial Dysfunction in Macrophages Prevents Osteonecrosis of the Jaw in Anti‐Resorptive Therapy

Advanced Science, EarlyView.
Schematic model showing the suggested mechanism that ZA induces classical activation of macrophages by impairing mitochondrial biofunction and inhibiting mitochondrial clearance to contribute to the pathological process of BRONJ. RAPA‐loaded nanoparticles ZDPR has shown potential in alleviating BRONJ lesions as well as treating osteoporosis or ...
Hang Zhang, Xin Shen, Haiyang Liu, Xinxi Yuan, Mumin Cao, Xuepeng Lv, Ziji Ling, Songsong Guo, Rongyao Xu, Xiang Li, Hongbing Jiang   +10 more
wiley   +1 more source

ARKbase: Antimicrobial Resistance Knowledgebase1.0. [PDF]

Nucleic Acids Res
Gambhir S, Pandey S, Bajetha H, Kaur J, Das A, Pranavathiyani G, Aggarwal R, Maity U, Dange S, Singh V, Zarkar M, Sankhdher R, Singh B, Seth S, Bhardwaj A.   +14 more
europepmc   +1 more source

The Gut Commensal Butyricimonas Virosa Modulates Gut Microbiota‐Dependent Thiamine Metabolism and Attenuates Mouse Steatotic Liver Disease

Advanced Science, EarlyView.
This study reveals that dietary stachyose enriches Butyricimonas virosa, effectively attenuating metabolic dysfunction‐associated steatotic liver disease (MASLD). Mechanistically, B. virosa enhances gut thiamine monophosphate synthesis, which elevates hepatic thiamine pyrophosphate levels.
Ningning He, Haoyu Wang, Zizhen Yang, Hui Li, Bei Liu, Kaiwei Chen, Zhinan Wu, Xinnan Zhao, Hewei Liang, Mengmeng Wang, Xiaofang Li, Yiyi Zhong, Haifeng Zhang, Liang Xiao, Karsten Kristiansen, Jixing Peng, Yuanqiang Zou, Shangyong Li   +17 more
wiley   +1 more source

Cell-to-Cell and Patient-to-Patient Variability in Antimicrobial Resistance. [PDF]

Microorganisms
Huang X, Huang J, Zhong CC, Wong MCS.
europepmc   +1 more source

Enhancing Binding by Electron Transfer at Heterointerfaces of Biochar‐Modified Hydrogel to Improve Utilization Efficiency of Wastewater Recovered Nutrients

Advanced Science, EarlyView.
Enhancing the utilization efficiency of nutrients recovered from wastewater is achieved through hydrogel modification by biochar. The strategy improves nutrient binding to hydrogels via electron transfer at heterointerfaces, thereby reducing nutrient release rate.
Hao Hu, Juncong Zou, Chenglin Zhang, Peng Li, Junnan Li, Yen Wah Tong, Jun Li, Yiliang He   +7 more
wiley   +1 more source