Results 131 to 140 of about 9,006,960 (303)

Potential and use of bacterial small RNAs to combat drug resistance: a systematic review

, 2017
Hung Chan,1,* Jeffery Ho,1,* Xiaodong Liu,1 Lin Zhang,1–3 Sunny Hei Wong,2,4 Matthew TV Chan,1 William KK Wu1,2 1Department of Anesthesia and Intensive Care, 2State Key Laboratory of Digestive Disease, LKS Institute of Health Sciences, 3School of ...
Liu X, Chan H, Wong SH, Ho J, Chan MT, Wu WK, Zhang L   +6 more
core  

Hydrogels Augmented With Artificial Sweeteners can Inhibit Multidrug‐Resistant Acinetobacter baumannii Growth and Biofilm Formation While Demonstrating Safety in Pre‐Clinical Pilot Human Trials

Advanced Healthcare Materials, EarlyView.
Using PVA–borax hydrogels as carriers for off‐the‐shelf artificial sweeteners to fight multidrug‐resistant A. baumannii. These soft, biocompatible hydrogels rapidly reduce bacterial viability within multidrug‐resistant A. baumannii biofilms by more than 99% within one hour and sustain antimicrobial activity over time, while demonstrating safety in both
Jie Han, Mohamed Soliman, Bin Zhang, Dominika Krawiel, Ronan R. McCarthy   +4 more
wiley   +1 more source

Antimicrobial Peptides: The Game-Changer in the Epic Battle Against Multidrug-Resistant Bacteria

Pharmaceuticals
The rapid progress of antibiotic resistance among bacteria has prompted serious medical concerns regarding how to manage multidrug-resistant (MDR) bacterial infections.
Helal F. Hetta, Nizar Sirag, Shumukh M. Alsharif, Ahmad A. Alharbi, Tala T. Alkindy, Alanoud Alkhamali, Abdullah S. Albalawi, Yasmin N. Ramadan, Zainab I. Rashed, Fawaz E. Alanazi   +9 more
doaj   +1 more source

How is Nanoarchitectonics Shaping Extracellular Vesicle Research?

Advanced Healthcare Materials, EarlyView.
The convergence of nanoarchitectonics and extracellular vesicle biology is reshaping next‐generation nanomedicine by enabling rationally designed nanostructures for enhanced EVs detection, engineering, and therapy. ABSTRACT Extracellular vesicles (EVs) have gained recognition as crucial mediators of cell‐to‐cell communication, holding immense potential
Madushani Dahanayake, Md Shahriar A. Hossain, Chia‐Hung Liu, Carlos Salomon, Yusuke Yamauchi, Mostafa Kamal Masud   +5 more
wiley   +1 more source

Optical Detection of Cellular Signals at Material Interfaces

Advanced Healthcare Materials, EarlyView.
Emerging functional materials are transforming optical detection of cellular signals. This review highlights optical techniques that exploit the unique optical properties of diverse materials to detect and quantify cellular electrical, chemical, and mechanical signals, and discusses key opportunities and challenges.
Xuchen Ren, Jitong Ren, Zixin Zhang, Koney Eungkon Kim, Francis L. Hong, Yuecheng Peter Zhou   +5 more
wiley   +1 more source

Stepwise implementation of an antimicrobial stewardship program in an open medical intensive care unit: Evaluation of antibiotic utilization and clinical outcomes

International Journal of Infectious Diseases
Objectives: Appropriate antibiotic use is crucial in intensive care units (ICUs) where patients are highly vulnerable to infection and antimicrobial resistance.
Si-Ho Kim, Min-Jin Bae, Sohui Lee, Gaeun Lee, Jaegon Ryu, Chunhwa Jung, Cheon-Hoo Jun, Yu Mi Wi   +7 more
doaj   +1 more source

PLL‐g‐HPA Hydrogel Microneedles Loaded With Rhoifolin Target Macrophages to Alleviate Fibroblast Senescence for Diabetic Wound Healing

Advanced Healthcare Materials, EarlyView.
Diabetic wound healing is hindered by a pathological crosstalk wherein elevated IL‐11 induces M1 macrophage polarization, leading to IL‐1β/IL‐6 release and subsequent fibroblast senescence via RAS/p38MAPK/p53/E2F1 signaling. Here, we develop a Gel@M‐Rho microneedle patch that delivers rhoifolin‐loaded, macrophage membrane‐coated nanoparticles to target
Jiewen Liao, Lin Gan, Li Lu, Lizhi Ouyang, Yuan Xiong, Fawwaz Al‐Smadi, Guandong Dai, Mohammad‐Ali Shahbazi, Bobin Mi, Mengfei Liu, Guohui Liu   +10 more
wiley   +1 more source

Chemical Strategies for Multistimuli Responsive Dynamic Covalent Materials in Regenerative Medicine

Advanced Healthcare Materials, EarlyView.
Multistimuli responsive dynamic covalent materials integrate reversible chemistry with the complex chemical, mechanical, and biochemical cues of regenerative environments. This review highlights chemical strategies based on orthogonal dynamic bonds, multicomponent networks, and hierarchical architectures to regulate mechanics, degradation, and ...
Saurabh Joshi, Matthew B. Baker, Dominik Schauenburg   +2 more
wiley   +1 more source

Antibiotic Resistance Pattern and Phylogenetic Groups of the Uropathogenic Escherichia coli Isolates Recovered from the Urinary Catheters of the Hospitalized Patients

Journal of Medical Microbiology and Infectious Diseases, 2016
Introduction: Almost 80% of nosocomial urinary tract infections (UTIs) are due to catheterization. Catheter-associated UTI (CAUTI) is the primary source for colonization of antibiotic-resistant pathogens, and uropathogenic Escherichia coli (UPEC) is the ...
Marziye Taheri, Moein Saleh, Amir Hesam Nemati, Mehdi Ariana, Esfandiar Shojaei, Masoud Mardani, Mohammad Katouli, Mohammad Pooya   +7 more
doaj  

Multidrug-Resistance Patterns and Predictors in Adult Acute Pyelonephritis: A Three-Year Cohort from a Tertiary Romanian Center with Derivation of the PYELO-MDR-Risk Score

Biomedicines
Background and Objectives: Multidrug-resistant (MDR) uropathogens are reshaping the empirical management of acute pyelonephritis, particularly in Eastern European centers.
Livia Stanga, Ovidiu Rosca, Iulia Georgiana Bogdan, Ciprian Ilie Roșca, Horia Silviu Branea, Camelia Vidița Gurban, Marius Papurica   +6 more
doaj   +1 more source