Results 221 to 230 of about 477,363 (346)

A Programmable Nanovaccine Platform Based on M13 Bacteriophage for Personalized Cancer Vaccine and Therapy

Advanced Materials, EarlyView.
A reprogrammed (RP) phage‐based nanovaccine platform has been developed that allows single‐step assembly with precise control over adjuvanticity, antigen density, and nanoparticle size. By enhancing TLR9 activation and neoantigen display, this platform enables a potent personalized vaccine targeting tumor‐specific neoantigens. When combined with immune
Shengnan Huang, Yanpu He, Allison Madow, Huaiyao Peng, Mirielle Griffin, Jifa Qi, Mantao Huang, Heather Amoroso, Riley Abrashoff, Nimrod Heldman, Angela M. Belcher   +10 more
wiley   +1 more source

IncN-R plasmid co-integration contributing to extensive drug resistance in <i>Escherichia coli</i> isolated from a canine prostatic abscess. [PDF]

Microbiol Spectr
Sroithongkham P, Leelapsawas C, Indra R, Payungporn S, Pinpimai K, Ponglowhapan S, Chanchaithong P.   +6 more
europepmc   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

Pharmacokinetic and pharmacodynamic integration and resistance analysis of cefquinome against <i>Streptococcus uberis in vitro</i> dynamic model. [PDF]

Front Microbiol
Li C, Wang J, Guo F, Zhang F, Chen B, Wang Z, Cao D, Yu Z.   +7 more
europepmc   +1 more source

Mesoporous Silica Nanoparticles in Biomedicine: Advances and Prospects

Advanced Materials, EarlyView.
Mesoporous silica nanoparticles offer unique properties like high surface area, tunable pores, and functionalization. They excel in drug delivery, tissue engineering, and stimuli‐responsive therapies, enabling targeted and controlled treatments. With roles in cancer therapy and diagnostics, their clinical translation requires addressing challenges in ...
Miguel Manzano, María Vallet‐Regí
wiley   +1 more source

Enhancing the therapeutical potential of metalloantibiotics using nano-based delivery systems. [PDF]

Beilstein J Nanotechnol
Llamedo A, Cano M, Soengas RG, García-Alonso FJ.   +3 more
europepmc   +1 more source

Spatially Controlled 3‐D Multiplexed Aptamer Patterning in Hydrogels

Advanced Materials Interfaces, EarlyView.
A hydrogel platform based on norbornene‐functionalized polyvinyl alcohol enables high‐resolution, 3‐D multiplexed patterning of DNA aptamers via two‐photon polymerization. Two distinct aptamers are covalently immobilized with single micron‐scale precision across the x, y, and z dimensions.
Kevin Roost, Annina Stuber, Kongchang Wei, Marine de Lapeyrière, Ke Yang, Valentin Gantenbein, Salvador Pané, Ivan Corbeski, Katharina Maniura‐Weber, Nako Nakatsuka   +9 more
wiley   +1 more source

Emergence of drug-resistant <i>Klebsiella pneumoniae</i> phylogroups (<i>K. quasipneumoniae</i> and <i>K. variicola</i>) causing human infections. [PDF]

Microbiol Spectr
Mishra K, Banerjee T, Yadav G, Kumar A, Pratap A, Chaurasiya S, Rakshit P.   +6 more
europepmc   +1 more source

Electrical Monitoring of Vibrio vulnificus–Host Cell Membrane Interactions in Simple and Complex Matrices

Advanced Materials Interfaces, EarlyView.
Supported lipid bilayers coupled with multielectrode array devices offer significant promise for pathogen–host cell membrane interaction studies. This work demonstrates, for the first time, the compatibility of this platform with biological fluids, in this case whole human blood, essential for any future point‐of‐care applications; as well as its ...
Alexandra Wheeler, Zixuan Lu, Jeremy Treiber, Alberto Salleo, Róisín M. Owens   +4 more
wiley   +1 more source

IITR00803: a benzoxazole-nitrothiophene small molecule with broad-spectrum antibacterial potential. [PDF]

Microbiol Spectr
Gupta R, Gaurav A, Pathania R.
europepmc   +1 more source