Results 81 to 90 of about 283,019 (191)

Celecoxib in breast cancer prevention and therapy. [PDF]

, 2018
Breast cancer has a high incidence worldwide. The results of substantial studis reveal that inflammation plays an important role in the initiation, development, and aggressiveness of many malignancies. The use of celecoxib, a novel NSAID, is repetitively
Cao, Wei, Hao, Qiongyu, Li, Jieqing, Vadgama, Jaydutt V, Wu, Yong   +4 more
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Hypoxia helps glioma to fight therapy [PDF]

, 2009
Despite major improvements in the surgical management the prognosis for patients bearing malignant gliomas is still dismal. Malignant gliomas are notoriously resistant to treatment and the survival time of patients is between 3-8 years for low-grade and
Amberger-Murphy, Verena
core   +1 more source

Evolutionary game theory of growth factor production: implications for tumour heterogeneity and resistance to therapies [PDF]

, 2013
Background: Tumour heterogeneity is documented for many characters, including the production of growth factors, one of the hallmarks of cancer. What maintains heterogeneity remains an open question that has implications for diagnosis and treatment, as ...
Archetti, M
core   +2 more sources

Causes and patterns of readmissions in patients with common comorbidities: retrospective cohort study [PDF]

, 2014
Objective To evaluate the primary diagnoses and patterns of 30 day readmissions and potentially avoidable readmissions in medical patients with each of the most common comorbidities. Design: Retrospective cohort study.
Bates, David W, Donzé, Jacques, Lipsitz, Stuart, Schnipper, Jeffrey L   +3 more
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JAK2 46/1 (GGCC) Haplotype: A Biomarker for Oncogenesis, Risk Stratification, and Drug Resistance in Myeloproliferative Neoplasms

Background: The JAK2 46/1 ("GGCC") haplotype, is an inherited genetic variation within the JAK2 gene locus that has become a focal point in research related to oncogenesis, particularly in myeloproliferative neoplasms (MPNs). Methods: We conducted a narrative review of landmark discoveries in hematological malignancies and JAK2 ...
Michela Perrone, Sara Sergio, Beatrice Pranzo, Amalia Tarantino, Giuseppina Loglisci, Rosella Matera, Davide Seripa, Michele Maffia, Nicola Di Renzo   +8 more
openaire   +1 more source

Research progress on immune checkpoint inhibitors in intrahepatic cholangiocarcinoma

Annals of Medicine
Background Intrahepatic cholangiocarcinoma (ICC) is a relatively uncommon but lethal neoplasm of the biliary tract. Evolving immunotherapy has important implications for the treatment of ICC.
Ziwen Yin, Lin Zhang, Jiexu Li, Haiyang Tan, Bingqi Ma   +4 more
doaj   +1 more source

Non-coding RNA transcripts, incredible modulators of cisplatin chemo-resistance in bladder cancer through operating a broad spectrum of cellular processes and signaling mechanism

Non-coding RNA Research
Bladder cancer (BC) is a highly frequent neoplasm in correlation with significant rate of morbidity, mortality, and cost. The onset of BC is predominantly triggered by environmental and/or occupational exposures to carcinogens, such as tobacco. There are
Mehrdad Hashem, Elaheh Mohandesi Khosroshahi, Melika Aliahmady, Morvarid Ghanei, Yasamin Soofi Rezaie, Yasamin alsadat Jafari, Fatemeh rezaei, Ramtin Khodaparast eskadehi, Kimia Kia Kojoori, faranak jamshidian, Noushin Nabavi, Mohsen Rashidi, Farzaneh Hasani Sadi, Afshin Taheriazam, Maliheh Entezari   +14 more
doaj   +1 more source

Epigenetic dispositions in ovarian clear cell carcinoma: a nexus of genomic, epigenetic, and metabolic alterations

Academia Oncology
Ovarian clear cell carcinoma (CCC) is a highly aggressive malignancy characterized by poor prognosis due to its resistance to chemotherapy, particularly in the advanced stages.
Ken Yamaguchi, Mengxin Jiang, Taito Miyamoto, Rin Mizuno, Mana Taki, Koji Yamanoi, Ryusuke Murakami, Junzo Hamanishi, Yuko Hosoe, Tsukasa Baba, Noriomi Matsumura, Ikuo Konishi, Shingo Fujii, Masaki Mandai   +13 more
doaj   +1 more source

Nanoplatform-based theranostics in glioblastoma: A promising frontier for precision oncology

Nano Trends
Glioblastoma (GBM) is the most aggressive primary brain neoplasm, characterized by a poor prognosis and resistance to standard treatments. The tumor's infiltrative characteristics and the tight blood-brain barrier (BBB) impede effective therapy.
Kesavarajan Govindarajan Karthikeyan, Balamurali Venkatesan, Natarajan Vaghesan, Pavithra Selvan, Sakthinarenderan Saikumar   +4 more
doaj   +1 more source

Evaluation of the activity of the immune system and age-related tissue markers in Turquoise killifish \ud (Nothobranchius furzeri, Jubb 1971) \ud and their role in cell ageing\ud [PDF]

, 2010
Currently the Turquoise Killifish is considered the best animal model suitable for aging research. \ud This annual fish, from south east Africa, shows an exceptionally adaptive behaviour to dry periods: indeed, due to this extreme environmental ...
Di Cicco, Emiliano, Rossi, Giacomo
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