Results 121 to 130 of about 1,232,228 (310)
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Bacteriophage-induced Antigenic Changes and Transduction of Drug Resistance in Salmonella Group E.
, 1955 Hisao Uetake, Tetsuji Nakagawa
openalex +2 more sources
Decrypting cancer's spatial code: from single cells to tissue niches
Molecular Oncology, EarlyView.Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik +4 more
wiley +1 more source
Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
DRUG RESISTANCE OF ENTERIC BACTERIA IV [PDF]
, 1964 EIKO KONDO, Susumu Mitsuhashi
openalex +1 more source
Molecular Oncology, EarlyView.This real‐world study of ROS1+ NSCLC highlights fusion diversity, treatment outcomes with crizotinib and lorlatinib, and in vitro experiments with resistance mechanisms. G2032R drives strong resistance to ROS1‐targeted TKIs, especially lorlatinib. Fusion partner location does not affect overall survival to crizotinib or lorlatinib. Findings support the
Fenneke Zwierenga +8 more
wiley +1 more source
Commentary: Malaria elimination in India and regional implications
Frontiers in Microbiology, 2018 Kwang Seung Park +5 more
doaj +1 more source
Drug Resistance of Staphylococci I. Transduction of Tetracycline Resistance with Phage Lysates Obtained from Multiply Resistant Staphylococci [PDF]
, 1965 Susumu Mitsuhashi +3 more
openalex +1 more source
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
Molecular Oncology, EarlyView.The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
EFFECT OF DRUG-RESISTANCE FACTOR R ON THE F PROPERTIES OF ESCHERICHIA COLI [PDF]
, 1964 Yukinori Hirota +3 more
openalex +1 more source