Results 241 to 250 of about 2,275,826 (357)

A CRISPR-based diagnostic tool to survey drug resistance in human African trypanosomiasis. [PDF]

Antimicrob Agents Chemother
Pérez Antón E, Dujeancourt-Henry A, Rotureau B, Glover L.   +3 more
europepmc   +1 more source

Impact of Stress‐Induced Hyperglycemia on In‐Hospital Medical Complications in Patients With Acute Stroke: From a Large‐Scale Nationwide Longitudinal Registry

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Aims This study aimed to explore the relationship between stress‐induced hyperglycemia (SIH) and in‐hospital medical complications in patients with acute stroke. Methods We enrolled 865,765 patients with acute stroke from the Chinese Stroke Center Alliance cohort.
Xintong Song, Yi Ju, Hongqiu Gu, Zhikai Zhu, Zixiao Li, Qian Zhang, Xingquan Zhao   +6 more
wiley   +1 more source

Impact of treatment history on drug resistance of metastatic colorectal cancer organoids. [PDF]

iScience
Huismans MA, Smabers LP, Brunner SR, van Hoeck A, Kaa DV, Franken IA, Wensink E, Koster J, Volckmann R, Kranenburg O, Koopman M, Snippert HJG, Roodhart JML.   +12 more
europepmc   +1 more source

Chromosomal instability and acquired drug resistance in multiple myeloma

, 2017
Wang Wang, Yi Zhang, Ruini Chen, Zhidan Tian, Yongpin Zhai, Siegfried Janz, Chunyan Gu, Ye Yang   +7 more
openalex   +2 more sources

The MMP‐9/TIMP‐1 Ratio and Concentrations of Osteopontin Are Elevated in Cerebrospinal Fluid of People With Multiple Sclerosis and Decrease After Autologous Hematopoietic Stem Cell Transplantation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To evaluate the utility of cerebrospinal fluid (CSF) biomarkers—matrix metalloproteinase‐9 (MMP‐9), tissue inhibitor of metalloproteinases‐1 (TIMP‐1), the MMP‐9/TIMP‐1 ratio, and osteopontin (OPN)—as indicators of blood–brain barrier (BBB) integrity and disease activity in people with relapsing–remitting multiple sclerosis (pwMS ...
Ivan Pavlovic, Ida Erngren, Kim Kultima, Anders Larsson, Malin Müller, Anna Wiberg, Joachim Burman   +6 more
wiley   +1 more source

Lysosomal Drug Sequestration Mediated by ABC Transporters and Drug Resistance. [PDF]

Pharmaceutics
Mlejnek P.
europepmc   +1 more source

Fibrinogen Changes Before and After Intravenous Thrombolysis as Predictors of Cerebral Injury and Clinical Outcomes in Acute Ischemic Stroke: A Multicenter Prospective Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma fibrinogen is essential in thrombosis and fibrinolysis, yet its dynamic changes pre‐ and post‐intravenous thrombolysis (IVT) for predicting brain injury severity and prognosis in acute ischemic stroke (AIS) patients remain unclear.
Wenhai Zhai, Yang Qu, Reziya Abuduxukuer, Kejia Zhang, Peng Zhang, Xin Tang, Huaimei Zhang, Lijuan Wang, Lichong Yang, Shuangxu Tan, Zhimei Yuan, Ce Han, Lili He, Yuping Zheng, Fenglan Zhao, Lijie Guo, Ligang Jiang, Jinfeng Li, Yongfei Jiang, Xuexia Zou, Dan Xu, Han Xu, Xiaojia Wang, Yingbin Qi, Xuefeng Hu, Yu Zhang, Zhen‐Ni Guo, Hang Jin, on behalf of the Biomarkers of Brain Injury Investigator Study Group   +28 more
wiley   +1 more source

The Genetic Diversity and Drug Resistance Patterns of HIV-1 Pol Gene in East Africa. [PDF]

Adv Virol
Kavuraya AN, Mselle T, Mpenda FN.
europepmc   +1 more source

Multi‐Omics Integration for Advancing Glioma Precision Medicine

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Gliomas are among the most malignant and aggressive tumors of the central nervous system, characterized by the absence of early diagnostic markers, poor prognosis, and a lack of effective treatments. Advances in high‐throughput technologies have facilitated a refined molecular classification of gliomas, incorporating genetic features. However,
Maria Guarnaccia, Valentina La Cognata, Giulia Gentile, Giovanna Morello, Sebastiano Cavallaro   +4 more
wiley   +1 more source

Recent Advances in Understanding the Clinical Implications of Heterogeneous Drug Resistance in <i>Klebsiella pneumoniae</i>. [PDF]

Infect Drug Resist
Fang J, Lai H, Chen H, Tao Z, Cheng N, Xiang T.   +5 more
europepmc   +1 more source