Results 291 to 300 of about 8,379,718 (351)
Unravelling drug resistance in leishmaniasis: genomic adaptations and emerging therapies. [PDF]
Bhusal CK, Sinha S, Kaur D, Sehgal R.
europepmc +1 more source
The glomerular filtration barrier (GFB) is the first step of blood filtration by the kidneys. The concerning increase of kidney diseases makes the development of new models essential. In this context, microphysiological glomerular filtration barriers focus on closely reproducing the physiological architecture of the in vivo GFB: podocytes, glomerular ...
Manon Miran+5 more
wiley +1 more source
Mechanism of USP11 regulated SIRT3/ROS in drug resistance of acute myeloid leukemia. [PDF]
Zhu P, Li H, Ge J, Zhou Z, Chen D, Li Q.
europepmc +1 more source
Intersection Between Local Anesthetics and Cancer Biology: What Now? Where Are We Going?
Local anesthetics (LAs), widely used in anesthesia, may also play a role in cancer treatment by inhibiting tumor growth, reducing metastasis, and enhancing immune responses. They modulate key pathways like AKT/mTOR and RAS/ERK while affecting angiogenesis and tumor innervation and the immune response.
Eduardo Nunez‐Rodriguez+3 more
wiley +1 more source
Research progress on m6A and drug resistance in gastrointestinal tumors. [PDF]
Xu Z+6 more
europepmc +1 more source
The novelty of this study showed that the injection of exosomes produced from ADMSCs in combination with Roflumilast poses a more favorable therapeutic outcome for CKD induced by Adriamycin, compared to therapy with exosomes or Roflumilast alone. Roflumilast and exosomes treatment lowered the expression of the apoptotic, fibrotic, and inflammatory ...
Mohamed Ali+5 more
wiley +1 more source
Exploring research advances and future trends in drug resistance in multiple myeloma: A comprehensive bibliometric analysis. [PDF]
Yang X+8 more
europepmc +1 more source
This study investigates the photosensitizing potential of Passiflora cincinnata in Antimicrobial Photodynamic Therapy (aPDT) against skin infection caused by Methicillin‐resistant Staphylococcus aureus (MRSA) in a senescent murine model. The P. cincinnata exhibits antimicrobial activity, with reduced bacterial load, lower leukocyte infiltration, and ...
Caroline Vieira Gonçalves+14 more
wiley +1 more source
Infrared (IR) light evokes distinct calcium and water transport responses in astrocytes, depending on stimulation duration and protocol. This study uses widefield imaging and pharmacology to reveal differential engagement of astroglial signaling pathways.
Wilson R. Adams+7 more
wiley +1 more source
Isorhamnetin Modulates Drug-Resistance-Related Biomarkers in Colon Cancer Cells. [PDF]
Radenković N+5 more
europepmc +1 more source