Results 271 to 280 of about 2,302,594 (308)
Some of the next articles are maybe not open access.
[Antimalarial drug resistance].
Medecine et maladies infectieuses, 2006Drug resistant malaria is mostly due to Plasmodium falciparum, the highly prevalent species in tropical Africa, Amazon, and Southeast Asia. P. falciparum is responsible for severe involvement of fever or anemia causing more than a million deaths per year.
Le Bras, J., Musset, L., Clain, J.
openaire +2 more sources
Resistance to Castration – Resistance to Drugs
2013Up to 70 % of newly diagnosed patients with advanced prostate cancer (PCa) will progress to castration-resistant prostate cancer (CRPC) and, in most cases (from 50 to 70 %), will develop hematogenous bone metastasis. Once PCa cells spread to the skeleton, cancer-related death becomes inevitable, with a death burden of more than 28,000 cases in 2012, in
openaire +2 more sources
DRUG RESISTANCE IN TUBERCULOSIS
Infectious Disease Clinics of North America, 1997Drug-resistant tuberculosis remains a worldwide problem. New laboratory methods have improved our ability to more rapidly identify resistant strains, but the most effective approach is to prevent the appearance of resistance by appropriate choice of antibiotics and directly-observed therapy.
L M, Parsons +3 more
openaire +2 more sources
2010
This chapter provides an overview of our current understanding of the mechanisms associated with the development of antimicrobial drug resistance, international differences in definitions of resistance, ongoing efforts to track shifts in drug susceptibility, and factors that can influence the selection of therapeutic intervention. The latter presents a
Marilyn, Martinez, Peter, Silley
openaire +2 more sources
This chapter provides an overview of our current understanding of the mechanisms associated with the development of antimicrobial drug resistance, international differences in definitions of resistance, ongoing efforts to track shifts in drug susceptibility, and factors that can influence the selection of therapeutic intervention. The latter presents a
Marilyn, Martinez, Peter, Silley
openaire +2 more sources
Current Opinion in Pulmonary Medicine, 2000
There is increasing concern in many countries about the problem of drug-resistant tuberculosis, particularly so because no new classes of drugs have been developed for the treatment of tuberculosis since the 1960s. Although drug resistance is thought to be fairly common in some countries and rare in others, the global extent of this condition is not ...
openaire +2 more sources
There is increasing concern in many countries about the problem of drug-resistant tuberculosis, particularly so because no new classes of drugs have been developed for the treatment of tuberculosis since the 1960s. Although drug resistance is thought to be fairly common in some countries and rare in others, the global extent of this condition is not ...
openaire +2 more sources
Trends in Microbiology, 1994
The mechanisms of action of antiviral drugs and of drug resistance are known in remarkable detail, partly because X-ray crystallographic structures are known for many target viral proteins. Resistance usually involves amino acid substitutions in the target protein that prevent drug binding or prevent an enzyme from accepting the drug as a substrate ...
openaire +2 more sources
The mechanisms of action of antiviral drugs and of drug resistance are known in remarkable detail, partly because X-ray crystallographic structures are known for many target viral proteins. Resistance usually involves amino acid substitutions in the target protein that prevent drug binding or prevent an enzyme from accepting the drug as a substrate ...
openaire +2 more sources
Molecular Genetics, Microbiology and Virology (Russian)
Genetic control of different pathways of drug-resistance formation in bacteria is presented. Possible molecular mechanisms of “new” genes integration into the genomes by horizontal gene transfer are discussed. This review may be valuable for physicians, veterinarians and scientific researches engaged in bacterial evolution.
openaire +1 more source
Genetic control of different pathways of drug-resistance formation in bacteria is presented. Possible molecular mechanisms of “new” genes integration into the genomes by horizontal gene transfer are discussed. This review may be valuable for physicians, veterinarians and scientific researches engaged in bacterial evolution.
openaire +1 more source
Drug Resistance Updates
Drug resistance, particularly those of anticancer drugs and antibiotics, poses a significant challenge in the treatment of diseases, severely compromising therapeutic efficacy and patient survival rates. In recent years, an increasing number of studies have highlighted the dual role of microbiota in either promoting or mitigating drug resistance.
Ru Jia +10 more
openaire +2 more sources
Drug resistance, particularly those of anticancer drugs and antibiotics, poses a significant challenge in the treatment of diseases, severely compromising therapeutic efficacy and patient survival rates. In recent years, an increasing number of studies have highlighted the dual role of microbiota in either promoting or mitigating drug resistance.
Ru Jia +10 more
openaire +2 more sources
Avoiding Drug Resistance in HIV Reverse Transcriptase
Chemical Reviews, 2021Maria E Cilento +2 more
exaly
Challenges and Opportunities in Cancer Drug Resistance
Chemical Reviews, 2021Richard A Ward +2 more
exaly