Results 81 to 90 of about 1,031,044 (237)

Murine Leukemia Viruses: Objects and Organisms

open access: yesAdvances in Virology, 2011
Murine leukemia viruses (MLVs) are among the simplest retroviruses. Prototypical gammaretroviruses encode only the three polyproteins that will be used in the assembly of progeny virus particles.
Alan Rein
doaj   +1 more source

ETHICS AND DRUG RESISTANCE

open access: yesBioethics, 2007
ABSTRACTThis paper reviews the dynamics behind, and ethical issues associated with, the phenomenon of drug resistance. Drug resistance is an important ethical issue partly because of the severe consequences likely to result from the increase in drug resistant pathogens if more is not done to control them.
openaire   +4 more sources

Effective Mixed-Type Tissue Crusher and Simultaneous Isolation of RNA, DNA, and Protein from Solid Tissues Using a TRIzol-Based Method

open access: yesJ
One of the major challenges of studying biomarkers in tumor samples is the low quantity and quality of isolated RNA, DNA, and proteins. Additionally, the extraction methods ideally should obtain macromolecules from the same tumor biopsy, allowing better ...
Kelly Karoline dos Santos   +11 more
doaj   +1 more source

Dual activity of PNGM-1 pinpoints the evolutionary origin of subclass B3 metallo-β-lactamases: a molecular and evolutionary study

open access: yesEmerging Microbes and Infections, 2019
Resistance to β-lactams is one of the most serious problems associated with Gram-negative infections. β-Lactamases are able to hydrolyze β-lactams such as cephalosporins and/or carbapenems.
Jung Hun Lee   +12 more
doaj   +1 more source

Drug Resistance in Tuberculosis

open access: yesAnnals of Saudi Medicine, 1990
Resistance to antituberculosis drugs is due to the occurrence of resistant mutants in the bacterial population even before exposure to these drugs. These mutations are chromosomal in origin. Resistance occurs when the bacterial population is large or when drugs are used alone. Potent drugs such as rifampicin, isoniazid and streptomycin are effective in
openaire   +4 more sources

Enigmatic exosomal connection in lung cancer drug resistance

open access: yesMolecular Therapy: Nucleic Acids
Lung cancer remains a significant global health concern with limited treatment options and poor prognosis, particularly in advanced stages. Small extracellular vesicles such as exosomes, secreted by cancer cells, play a pivotal role in mediating drug ...
Sambit K. Patra   +4 more
doaj  

DRUG-RESISTANCE OF BACTERIS

open access: yesThe KITAKANTO Medical Journal, 1963
In the field study many types of drug-resistant E. coli, Shigella and Citrobacter were isolated by this laboratory. And seven types of transmissible drug-resistance factor were obtained; R(TC) R(SM), R(CM. TC), R(SM. SA), R(CM. SM SA), R(TC. SM. SA) and R(CM. TC.SM. SA). The R(CM) factor was segregated from (CM.
openaire   +5 more sources

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